Leupeptin Trifluoroacetate Salt
Leupeptin Trifluoroacetate Salt is used as inhibitor for trypsin, plasmin, papain, and cathepsin B.
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|Alternate Names||Acetyl-Leu-Leu-Arg-al;Acetyl-Leu-Leu-Arg-al trifluoroacetate salt|
|Application Notes||Leupeptin Trifluoroacetate Salt is used as inhibitor for trypsin, plasmin, papain, and cathepsin B.|
|Base Catalog Number||195623|
|Biochemical Physiological Actions||Inhibitor of serine and cysteine proteases. Inhibits plasmin, trypsin, papain, calpain, and cathepsin B. Does not inhibit pepsin, cathepsins A and D, thrombin, or α-chymotrypsin. There have been numerous studies using leupeptin to protect against hearing loss caused by acoustic overstimulation or the ototoxic antibiotic gentamicin. (Loss of cochlear hair cells is believed to be mediated by calpain.)|
|Molecular Weight||540.585 g/mol|
|Personal Protective Equipment||Eyeshields, Gloves, respirator filter|
|Typical Working Concentration||10-100 uM|