Ristocetin Sulfate Salt

Application Notes

Ristocetin A has platelet aggregating activity and has been used in platelet aggregation studies. Studies have demonstrated that Ristocentin A dimerizes and creates two binding sites for cell wall peptides.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic | Clotting Factors

SKU	02195489-CF
Alternate Names	Ristomycin monosulfate
Application Notes	Ristocetin A has platelet aggregating activity and has been used in platelet aggregation studies. Studies have demonstrated that Ristocentin A dimerizes and creates two binding sites for cell wall peptides.
Base Catalog Number	195489
Biochemical Physiological Actions	Ristocetin activates platelets. Ristocetin-induced platelet agglutination (RIPA) is decreased in patients undergoing chronic hemodialysis. Together with increased plasma glycocalicin levels (a product of enzymatic cleavage of GPIb), RIPA may contribute to diminished platelet adhesion to vascular subendothelium and increased bleeding associated with uremia. Addition of ristocetin and vWf caused specific agglutination of rGPIbα-liposomes suporting the potential use of rGPIbα-liposomes to enhance platelet function in vivo and support hemostasis in thrombocytopenic individuals.
CAS #	11140-99-1
EC Number	215-770-5
Format	Powder
Molecular Formula	C95H110N8O44·H2SO4
Molecular Weight	2067.937 g/mol
Personal Protective Equipment	Eyeshields, Gloves, Respirator filter
Purity	≥90% Ristocetin A
RTECS Number	VJ8580000
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.