Ethylene glycol-bis-(Β-amino-ethylether)-N,N,N′,N′-tetraacetic acid
Ethylene Glycol-Bis-(Β-Amino-Ethylether)-N,N,N′,N′-Tetraacetic Acid
Application Notes
Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent for determination of calcium in the presence of magnesium; it can also detect cadmium in the presence of zinc. It is also useful for the removal of heavy metal ions in biological systems. It is shown to activate Ca2+- stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, matrix metalloproteinases.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Chelating agent
SKU | 02194823-CF |
Alternate Names | EGTA; GEDTA; O,O'-bis(2-aminoethyl)ethyleneglycol-N,N,N',N'-tetraacetic acid; Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetracetic acid; Egtazic acid; Ethylene-bis(oxyethylenenitrilo)tetraacetic acid; Glycol ether diamine tetraacetic acid |
Application Notes | Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent for determination of calcium in the presence of magnesium; it can also detect cadmium in the presence of zinc. It is also useful for the removal of heavy metal ions in biological systems. It is shown to activate Ca2+- stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, matrix metalloproteinases. |
Base Catalog Number | 194823 |
Beilstein Registry Number | 1717370 |
CAS # | 67-42-5 |
EC Number | 200-651-2 |
Format | Powder |
Grade | Molecular Biology Grade |
Molecular Formula | C14H24N2O10 |
Molecular Weight | 380.35 g/mol |
Personal Protective Equipment | Eyeshields, Gloves, Respirator filter |
pKa | < 2, 2.7, 8.8, and 9.5 (Lit.) |
Purity | ≥97% |
RTECS Number | AH3760000 |
Typical Working Concentration | as a metalloprotease inhibitor (effective concentration is typically 1 to 10 µM) |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |