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Staurosporine, molecular biology reagent, ≥98%
Product Description
Staurosporine
Application Notes
Staurosporine from Streptomyces sp. was used to induce cell death in MDCK, 293T, Vero, HeLa, and Swiss Webster primary macrophage cells. It was used to study the effect of caspase activation on human sperm quality.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Specifications
SKU | 02194805-CF |
Alternate Names | Antibiotic AM-2282 |
Application Notes | Staurosporine from Streptomyces sp. was used to induce cell death in MDCK, 293T, Vero, HeLa, and Swiss Webster primary macrophage cells. It was used to study the effect of caspase activation on human sperm quality. |
Base Catalog Number | 194805 |
Beilstein Registry Number | 1060573 |
Biochemical Physiological Actions | Potent inhibitor of phospholipid/calcium-dependent protein kinase. Inhibits the upregulation of VEGF expression in tumor cells.Partially reverses MDR, sensitizing cells with MDR phenotype to cytotoxic agents. Inhibits Pgp phosphorylation. However, functional significance of Pgp phosphorylation is ill defined. |
CAS # | 62996-74-1 |
Format | Film |
Grade | Molecular Biology Grade |
Hazard Statements | H340-H350 |
Molecular Formula | C28H26N4O3 |
Molecular Weight | 466.541 g/mol |
Personal Protective Equipment | Eyeshields, full-face particle respirator , Gloves, respirator cartridge, respirator filter |
Purity | ≥98% |
Safety Symbol | GHS08 |
Source | Streptomyces sp. |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Citations
Documents
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Datasheet
Datasheet
Material Safety Datasheet
Material Safety Datasheet
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