Cart
 
Inquire

Actinomycin D, cell culture reagent

Actinomycin D, cell culture reagent

Key features and details

Actinomycin D

SKU: 02194525-CF

Synonyms
Dactinomycin; Actinomycin D; actinomycin-[thr-val-pro-sar-meval]; meractinomycin; actinomycin AIV; actinomycin IV; actinomycin C1; actinomycin X1; NSC-3053; Cosmegen
CAS Number:
50-76-0
Molecular Formula:
C62H86N12O16
Molecular Weight:
1255.438 g/mol
EC Number:
200-063-6
MDL Number:
MFCD00005033
Product Description

Actinomycin D

Application Notes

Actinomycin D is an antineoplastic antibiotic that inhibits cell proliferation with wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm's tumour and the sarcomas.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications
SKU 02194525-CF
Alternate Names Dactinomycin; Actinomycin D; actinomycin-[thr-val-pro-sar-meval]; meractinomycin; actinomycin AIV; actinomycin IV; actinomycin C1; actinomycin X1; NSC-3053; Cosmegen
Application Notes Actinomycin D is an antineoplastic antibiotic that inhibits cell proliferation with wide-ranging applications ranging from a selection agent in cell culture, use in studies of suppressing HIV-replication and programmed cell death of PC12 cells, and as an antibiotic in treatment of various malignant neoplasms, including Wilm's tumour and the sarcomas.
Base Catalog Number 194525
Biochemical Physiological Actions Actinomycin D inhibits the proliferation of cells by forming a stable complex with double-stranded DNA, inhibiting DNA-primed RNA synthesis and causing single-stranded breaks in DNA. It has been shown to be an inhibitor of the minus-strand transfer step in reverse transcriptase.
CAS # 50-76-0
EC Number 200-063-6
Format Crystalline
Grade Cell Culture Grade
Hazard Statements H300
Melting Point 467 to 469° F (decomposes) (NTP, 1992)
Molecular Formula C62H86N12O16
Molecular Weight 1255.438 g/mol
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge
Purity ~98%
Refractive Index 1.656(lit.)
RTECS Number AU1575000
Safety Symbol GHS06
Solubility Soluble at 50° F (NTP, 1992)
Typical Working Concentration cell culture applications at 1µg/mL.
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure 0 mm Hg at 25 deg C (est)
Citations
Documents

Certificate of Analysis

Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis

Datasheet

Datasheet

Material Safety Datasheet

Material Safety Datasheet
en_AE
Material Safety Datasheet
de_AT
Material Safety Datasheet
en_AU
Material Safety Datasheet
fr_BE
Material Safety Datasheet
en_CA
Material Safety Datasheet
fr_CA
Material Safety Datasheet
de_CH
Material Safety Datasheet
cn_ZH
Material Safety Datasheet
de_DE
Material Safety Datasheet
es_ES
Material Safety Datasheet
en_EU
Material Safety Datasheet
fi_FI
Material Safety Datasheet
fr_FR
Material Safety Datasheet
tw_ZH
Material Safety Datasheet
en_ID
Material Safety Datasheet
en_IE
Material Safety Datasheet
en_IN
Material Safety Datasheet
ja_JP
Material Safety Datasheet
de_LI
Material Safety Datasheet
de_LU
Material Safety Datasheet
en_MT
Material Safety Datasheet
es_MX
Material Safety Datasheet
no_NO
Material Safety Datasheet
pt_PT
Material Safety Datasheet
sv_SE
Material Safety Datasheet
en_US