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Colistin sulphate salt, ≥15,000 U/mg

Colistin sulphate salt, ≥15,000 U/mg

$34.75

Key features and details

  • Mixture of cyclic polypeptides colistin A and B
  • Effective against most Gram-negative bacilli
  • Used as a polypeptide antibiotic.

SKU: 02194157-CF

Synonyms
Polymyxin E
CAS Number:
1264-72-8
Molecular Weight:
1253.527 g/mol
EC Number:
215-034-3
MDL Number:
MFCD00146495
Product Description

Colistin Sulphate Salt

Application Notes

Colistin sulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant haemagglutination and antibiotic resistance in certain organisms such as A. baumannii. It has been used to study hephrotoxicity in the rat kidney, and MICs, time-kill kinetics, and postantibiotic effect (PAE) against Pseudomonas aeruginosa.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 02194157-CF
Alternate Names Polymyxin E
Application Notes Colistin sulfate is used to permeabilize bacterial cell membranes and to study mannose-resistant haemagglutination and antibiotic resistance in certain organisms such as A. baumannii. It has been used to study hephrotoxicity in the rat kidney, and MICs, time-kill kinetics, and postantibiotic effect (PAE) against Pseudomonas aeruginosa.
Base Catalog Number 194157
Biochemical Physiological Actions Mode of Action: Binds to lipids on the cell cytoplasmic membrane of Gram-negative bacteria and disrupts the cell wall integrity. Antimicrobial spectrum: Gram-negative bacteria. It is proposed that renal reabsorption of colistin may involve organic cation transporters and peptide transporters and that the process is sensitive to pH.
CAS # 1264-72-8
EC Number 215-034-3
Hazard Statements H301
Molecular Weight 1253.527 g/mol
Personal Protective Equipment Eyeshields, Faceshields, Gloves, respirator cartridges
RTECS Number TR1500000
Specific Activity ≥15,000 u/mg
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations
Documents

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Datasheet

Datasheet

Material Safety Datasheet

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