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Miconazole

Miconazole

$46.30

Key features and details

Miconazole

SKU: 02193915-CF

Synonyms
1-[2,4-Dichloro-β-([2,4-dichlorobenzyl]oxy)phenethyl]imidazole; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; Monistat; Daktarin IV; Miconazolo; Miconazolum; Dactarin; Miconazol; Minostate; Brentan; Florid(nitrate)
CAS Number:
22916-47-8
Molecular Formula:
C18H14Cl4N2O
Molecular Weight:
416.123 g/mol
EC Number:
245-324-5
Product Description

Miconazole

Application Notes

Miconazole is an imidazole antifungal agent that is used topically and by intravenous infusion. It is used to inhibit cytochrome P450 and to study automated luminescence-based cytochrome P450 profiling

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Anti-fungal agent

Specifications
SKU 02193915-CF
Alternate Names 1-[2,4-Dichloro-β-([2,4-dichlorobenzyl]oxy)phenethyl]imidazole; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; Monistat; Daktarin IV; Miconazolo; Miconazolum; Dactarin; Miconazol; Minostate; Brentan; Florid(nitrate)
Application Notes Miconazole is an imidazole antifungal agent that is used topically and by intravenous infusion. It is used to inhibit cytochrome P450 and to study automated luminescence-based cytochrome P450 profiling
Base Catalog Number 193915
Biochemical Physiological Actions Miconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for ergosterol biosynthesis. The inhibition of ergosterol results in increased cellular permeability causing leakage of cellular contents. Miconazole may also inhibit endogenous respiration, interact with phospholipids in the cell membrane, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and interfere with triglyceride and phospholipid biosynthesis.
CAS # 22916-47-8
EC Number 245-324-5
Format Powder
Melting Point 159-163 °C
Molecular Formula C18H14Cl4N2O
Molecular Weight 416.123 g/mol
RTECS Number NI4770000
Solubility Water Solubility1g/100mL (20 °C)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations
Documents

Certificate of Analysis

Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis

Datasheet

Datasheet

Material Safety Datasheet

Material Safety Datasheet
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