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Folinic acid calcium salt, pentahydrate

Folinic acid calcium salt, pentahydrate

$41.15

Key features and details

Folinic Acid Calcium Salt, Pentahydrate

SKU: 02191504-CF

Synonyms
5-Formyl-5,6,7,8-tetrahydrofolic acid calcium salt; 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid calcium salt; 5-HCO-H4PteGlu; Calcium folinate; Citrovorum factor calcium salt; Leucovorin calcium salt; N5-Formyl-5,6,7,8- tetrahydropteroyl-L-glutamic acid calcium salt; CF; N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4- hydroxy-6- pteridinyl) methyl] amino] benzoyl] glutamic acid calcium salt; N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl) methyl] amino] benzoyl]-Lglutamic acid calcium salt
CAS Number:
1492-18-8
Molecular Formula:
C20H21N7O7Ca
Molecular Weight:
511.508 g/mol
Beilstein Registry Number:
5723924
EC Number:
216-082-8
Product Description

Folinic Acid Calcium Salt, Pentahydrate

Application Notes

Folinic Acid Calcium Salt, Pentahydrate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. In medicine, calcium folinate is used after treatment with methotrexate to reduce the toxicity of the methotrexate. Calcium folinate is also used to enhance the cytotoxic effect of 5-fluorouracil in the treatment of cancer.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 02191504-CF
Alternate Names 5-Formyl-5,6,7,8-tetrahydrofolic acid calcium salt; 5-Formyl-5,6,7,8-tetrahydropteroyl-L-glutamic acid calcium salt; 5-HCO-H4PteGlu; Calcium folinate; Citrovorum factor calcium salt; Leucovorin calcium salt; N5-Formyl-5,6,7,8- tetrahydropteroyl-L-glutamic acid calcium salt; CF; N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4- hydroxy-6- pteridinyl) methyl] amino] benzoyl] glutamic acid calcium salt; N-[4-[[(2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl) methyl] amino] benzoyl]-Lglutamic acid calcium salt
Application Notes Folinic Acid Calcium Salt, Pentahydrate offsets the effects of folic acid antagonists that act by binding dihydrofolate reductase and blocking the conversion of folic acid to tetrahydrofolate. In medicine, calcium folinate is used after treatment with methotrexate to reduce the toxicity of the methotrexate. Calcium folinate is also used to enhance the cytotoxic effect of 5-fluorouracil in the treatment of cancer.
Base Catalog Number 191504
Beilstein Registry Number 5723924
Biochemical Physiological Actions Intermediate product of the metabolism of folic acid; the active form into which that acid is converted in the body, ascorbic acid being a necessary factor in the conversion process.
CAS # 1492-18-8
EC Number 216-082-8
Format Powder
Hazard Statements H315-H317-H319-H334-H335
Molecular Formula C20H21N7O7Ca
Molecular Weight 511.508 g/mol
RTECS Number MA0600500
Safety Symbol GHS07, GHS08
Solubility DMSO « 1 (mg/mL)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations
Documents

Certificates of Analysis

Certificates of Analysis
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Certificates of Analysis
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Certificates of Analysis
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Material Safety Data Sheet

Material Safety Data Sheet
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Material Safety Data Sheet
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Material Safety Data Sheet
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Material Safety Data Sheet
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Material Safety Data Sheet
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Material Safety Data Sheet
English (United States)