Desmosine

Application Notes

Desmosine is responsible for the cross-linking of elastin leading to the formation of insoluble fibers. Urinary excretion of desmosine is a useful indicator of elastin breakdown resulting from increased elastase activity. It also acts as a biomarker of elastin degradation in chronic obstructive.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Cross-linking of elastin

SKU	02191378-CF
Application Notes	Desmosine is responsible for the cross-linking of elastin leading to the formation of insoluble fibers. Urinary excretion of desmosine is a useful indicator of elastin breakdown resulting from increased elastase activity. It also acts as a biomarker of elastin degradation in chronic obstructive.
Base Catalog Number	191378
CAS #	11003-57-9
Format	Solid
Molecular Weight	526.611 g/mol
Preparation Method	Desmosine is prepared according to the method of Starcher et al. from hydrolyzed neck ligament by solvent extraction and chromatography on Dowex 50.
Purity	99%
Source	Bovine Neck Ligament
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.