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Neomycin sulfate, USP
Specifications
SKU | 02180610-CF |
Application Notes | Neomycin Trisulfate is produced by Streptomyces containing a minimum of 85% neomycin B. It has been used as a selection agent for prokaryotic cells transformed using the neo selectable marker gene, and to study ototoxic side effects of antibiotics, platelet-derived growth factor responses in certain fibroblasts, and extraction of Nuclear Phosphatidylinositol 4,5-Bisphosphate-Interacting Proteins. |
Base Catalog Number | 180610 |
Biochemical Physiological Actions | Mode of action: This product acts by binding to the 30S and 50S subunits, causing miscoding and inhibiting initiation and elongation during protein synthesis. Neomycin also blocks voltage-sensitive Ca2+ channels without affecting the Na+/Ca2+ antiporter in neurons. |
CAS # | 1405-10-3 |
EC Number | 215-773-1 |
Format | Powder |
Grade | USP |
Hazard Statements | H317-H334 |
Molecular Formula | C23H46N6O13 • 3H2SO4 |
Molecular Weight | 908.9 |
Personal Protective Equipment | dust mask, Eyeshields, Faceshields, Gloves |
pH | 5-7.5 |
Safety Symbol | GHS08 |
Solubility | H2O: soluble50 mg/mL |
Specific Activity | ≥600 µg/mg |
Typical Working Concentration | It is recommended for use in cell culture applications at 50 mg/L. |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Documents
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Material Safety Datasheet
Material Safety Datasheet
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