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Sulfamethoxazole is used for treating various types of bacterial infections, including urinary tract infections, acute worsening of chronic bronchitis, and ear infections. In addition it can be used as an alternative to amoxicillin-based antibiotics to treat sinusitis.
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|Alternate Names||4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide; N1-(5-Methylisoxazol-3-yl)sulfanilamide; 5-Methyl-3-sulfanilamidoisoxazole; 3-Sulfanilamido-5-methylisoxazole; 3-(p-Aminophenylsulfonamido)-5-methylisoxazole; Sulfisomezole; Sulfamethylisoxazole; Sulfamethoxizole|
|Application Notes||Sulfamethoxazole is used for treating various types of bacterial infections, including urinary tract infections, acute worsening of chronic bronchitis, and ear infections. In addition it can be used as an alternative to amoxicillin-based antibiotics to treat sinusitis.|
|Base Catalog Number||156711|
|Beilstein Registry Number||6732984|
|Biochemical Physiological Actions||Sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Mode of Action: Inhibits folic acid synthesis in prokaryotes. Anti-microbial Spectrum: Gram positive, Gram negative, Chlamydia. Mode of Resistance: Alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.|
|Melting Point||333° F (NTP, 1992)|
|Molecular Weight||253.276 g/mol|
|Personal Protective Equipment||Dust mask, Eyeshields, Faceshields, Gloves|
|Vapor Pressure||6.93X10-8 mm Hg at 25 deg c (est)|