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Sulfamethazine, sodium salt

Sulfamethazine, sodium salt

$53.25

Key features and details

Sulfamethazine Sodium Salt

SKU: 02156709-CF

Synonyms
4-Amino-N-[4,6-dimethyl-2-pyrimidinyl]benzenesulfonamide
CAS Number:
1981-58-4
Molecular Formula:
C12H13N4O2SNa
Molecular Weight:
300.312 g/mol
EC Number:
217-840-0
MDL Number:
MFCD00068333
Product Description

Sulfamethazine Sodium Salt

Application Notes

Sulfamethazine is an antibiotic used to clinically treat bronchitis, prostatitis and urinary tract infections. It is used in disposition and depletion kinetic studies. It is used to develop detection techniques for quantification in fluids such as cows’ milk, honey and swine urine.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications
SKU 02156709-CF
Alternate Names 4-Amino-N-[4,6-dimethyl-2-pyrimidinyl]benzenesulfonamide
Application Notes Sulfamethazine is an antibiotic used to clinically treat bronchitis, prostatitis and urinary tract infections. It is used in disposition and depletion kinetic studies. It is used to develop detection techniques for quantification in fluids such as cows’ milk, honey and swine urine.
Base Catalog Number 156709
Biochemical Physiological Actions Sulfamethazine is an antimicrobial sulfur drug that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfamethazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It induces CYP3A4 expression and is acetylated by N-acetyltransferase. It exhibits sex dependent pharmacokinetics, metabolized by the male specific isoform CYP2C11. Sulfamethazine is bacteriostatic.
CAS # 1981-58-4
Density 1.4655 g/cu cm
EC Number 217-840-0
Format Powder
Hazard Statements H302
Melting Point 176 deg C (also reported as mp 178-179 deg C; mp 198-199 deg C; mp 205-207 deg C)
Molecular Formula C12H13N4O2SNa
Molecular Weight 300.312 g/mol
RTECS Number WO9300000
Safety Symbol GHS07
Solubility In <a class="pubchem-internal-link CID-962" href="https://pubchem.ncbi.nlm.nih.gov/compound/water">water</a>, 1.50X10+3 mg/L at 29 deg C and 1.92X10+3 mg/L at 37 deg C; solubility increases with increasing pH
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure 6.82X10-9 mm Hg at 25 deg C (est)
Documents

Certificate of Analysis

Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis

Material Safety Datasheet

Material Safety Datasheet
en_AU
Material Safety Datasheet
en_US