Metronidazole

Application Notes

Metronidazole suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. Further studies show that Metronidazole has been used to repress the growth of gram-negative anaerobes belonging to the Bacteroides and Fusobacterium, and gram-positive anaerobes such as peptostreptococcus and Clostridia. The advantages of this antibiotic is that it affects a high percentage of gram-negative bacteria and has greater tissue penetration. Furthermore, the gene hefA codes for the TolC efflux pump in Helicobacter pylori which is resistant to Metronidazole.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotics | Chromatography | Antibacterial

SKU	02155710-CF
Alternate Names	2-Methyl-5-nitroimidazole-1-ethanol; 1-(2-Hydroxyethyl)-2-methyl-5-nitroimidazole; 1-(b-Ethylol)-2-methyl-5-nitro-3-azapyrrole
Application Notes	Metronidazole suppress protozoans such as Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis. Further studies show that Metronidazole has been used to repress the growth of gram-negative anaerobes belonging to the Bacteroides and Fusobacterium, and gram-positive anaerobes such as peptostreptococcus and Clostridia. The advantages of this antibiotic is that it affects a high percentage of gram-negative bacteria and has greater tissue penetration. Furthermore, the gene hefA codes for the TolC efflux pump in Helicobacter pylori which is resistant to Metronidazole.
Base Catalog Number	155710
Beilstein Registry Number	611683
CAS #	443-48-1
EC Number	207-136-1
Format	Powder
Hazard Statements	H351
Melting Point	316 to 320° F (NTP, 1992)
Molecular Formula	C6H9N3O3
Molecular Weight	171.156 g/mol
Personal Protective Equipment	Dust mask, Eyeshields, Gloves
pH	pH of saturated aq soln is 5.8
RTECS Number	NI5600000
Safety Symbol	GHS08
Solubility	>25.7 [ug/mL]
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure	3.1X10-7 mm Hg at 25 deg C (est)