Cart
 
In Stock

Bumetanide

Bumetanide

$70.90

Key features and details

Bumetanide

SKU: 02154263-CF

Synonyms
Ro 10-6338; 3-(aminosulfonyl)-5-(butylamino)- 4-phenoxybenzoic acid; 3-(butylamino)-4-phenoxy- 5-sulfamoylbenzoic acid
CAS Number:
28395-03-1
Molecular Formula:
C17H20N2O5S
Molecular Weight:
364.416 g/mol
EC Number:
249-004-6
MDL Number:
MFCD00078949
Product Description

Bumetanide

Application Notes

Bumetanide has been used to probe the role of prostaglandin E2 in the regulation of chloride secretion across porcine endometrial epithelial cells. A study of the effects of bumetanide application and subsequent sodium potassium chloride cotransporter (NKCC1) inhibition in cultured liver cells has indicated increased α1-smooth muscle actin expression in 2-day-cultured hepatic stellate cells. An investigation of lactacidosis treatment of suspended G6 glial cells with bumetanide included at 0.1 mM has shown diminished cell swelling due to lactacidosis.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 02154263-CF
Alternate Names Ro 10-6338; 3-(aminosulfonyl)-5-(butylamino)- 4-phenoxybenzoic acid; 3-(butylamino)-4-phenoxy- 5-sulfamoylbenzoic acid
Application Notes Bumetanide has been used to probe the role of prostaglandin E2 in the regulation of chloride secretion across porcine endometrial epithelial cells. A study of the effects of bumetanide application and subsequent sodium potassium chloride cotransporter (NKCC1) inhibition in cultured liver cells has indicated increased α1-smooth muscle actin expression in 2-day-cultured hepatic stellate cells. An investigation of lactacidosis treatment of suspended G6 glial cells with bumetanide included at 0.1 mM has shown diminished cell swelling due to lactacidosis.
Base Catalog Number 154263
Biochemical Physiological Actions Inhibitor of Na+/K+/Cl- cotransporter.
CAS # 28395-03-1
EC Number 249-004-6
Format Powder
Melting Point 230-231
Molecular Formula C17H20N2O5S
Molecular Weight 364.416 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Purity ≥99%
RTECS Number DG4910000
Solubility >54.7 [ug/mL]
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations
Documents

Certificate of Analysis

Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis

Datasheet

Datasheet

Material Safety Datasheet

Material Safety Datasheet
en_AE
Material Safety Datasheet
de_AT
Material Safety Datasheet
en_AU
Material Safety Datasheet
fr_BE
Material Safety Datasheet
nl_BE
Material Safety Datasheet
en_CA
Material Safety Datasheet
fr_CA
Material Safety Datasheet
de_CH
Material Safety Datasheet
fr_CH
Material Safety Datasheet
it_CH
Material Safety Datasheet
cn_ZH
Material Safety Datasheet
zh_CN
Material Safety Datasheet
de_DE
Material Safety Datasheet
es_ES
Material Safety Datasheet
en_EU
Material Safety Datasheet
fi_FI
Material Safety Datasheet
fr_FR
Material Safety Datasheet
en_GB
Material Safety Datasheet
tw_HK
Material Safety Datasheet
tw_ZH
Material Safety Datasheet
en_ID
Material Safety Datasheet
en_IE
Material Safety Datasheet
en_IN
Material Safety Datasheet
it_IT
Material Safety Datasheet
ja_JP
Material Safety Datasheet
ko_KR
Material Safety Datasheet
de_LI
Material Safety Datasheet
de_LU
Material Safety Datasheet
en_MT
Material Safety Datasheet
es_MX
Material Safety Datasheet
nl_NL
Material Safety Datasheet
no_NO
Material Safety Datasheet
pt_PT
Material Safety Datasheet
ru_RU
Material Safety Datasheet
sv_SE
Material Safety Datasheet
tw_TW
Material Safety Datasheet
en_US