N-Acetyl-Asp-Glu may act as a neurotransmitter in the retinohypothalamic tract.
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|Alternate Names||N-Acetyl-Aspartic Acid-glutamic acid-OH; N-Ac-D-E; NAAG; Spaglumic acid|
|Application Notes||N-Acetyl-Asp-Glu may act as a neurotransmitter in the retinohypothalamic tract.|
|Base Catalog Number||153036|
|Biochemical Physiological Actions||Endogenous neurotransmitter localized to neurons with high affinity for metabotropic glutamate receptors, mGluR3. It is an antagonist at NMDA receptors. Catabolized by carboxypeptidase II, which is expressed on astrocyte membranes, to N-acetylaspartate and glutamate.|
|Molecular Weight||304.255 g/mol|
|Optical Rotation||[α]22/D −34.5°, c = 1.1 in H2O(lit.)|
|Personal Protective Equipment||Dust mask, Eyeshields, Gloves|