Oligomycin

Application Notes

Oligomycin is used as antibiotic which inhibits respiration in mitochondria. It inhibits ATP synthase by blocking its proton channel (F0 subunit), which is necessary for oxidative phosphorylation of ADP to ATP (energy production).

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

SKU	02151786-CF
Alternate Names	Olivomycin; Aburamycin
Application Notes	Oligomycin is used as antibiotic which inhibits respiration in mitochondria. It inhibits ATP synthase by blocking its proton channel (F0 subunit), which is necessary for oxidative phosphorylation of ADP to ATP (energy production).
Base Catalog Number	151786
Beilstein Registry Number	7615308
Biochemical Physiological Actions	It inhibits mitochondrial ATPase and phosphoryl group transfer.
CAS #	1404-19-9
EC Number	215-767-9
Format	Powder
Formulation Details	A mixture of oligomycin A; B and C in an approximate ratio of 60:30:10 Oligomycin A: C45H74O11 Oligomycin B: C45H72O12 Oligomycin C: C45H74O10
Hazard Statements	H301
Molecular Weight	791.076 g/mol
Personal Protective Equipment	Dust mask, Eyeshields, Faceshields, Gloves
RTECS Number	RK3325000
Safety Symbol	GHS06
Source	Streptomyces diastatochromogenes
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.