Glutamic Pyruvic Transaminase
Glutamic-pyruvic transaminase (GPT) is used as a marker of liver disease due to the release of GPT into the blood following liver cell necrosis.
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Marker for liver disease
|Alternate Names||L-Alanine: 2-Oxoglutarate Aminotransferase; Alanine Aminotransferase (catalytic concentration); GPT; serum glutamic pyruvic transaminase; SGPT|
|Application Notes||Glutamic-pyruvic transaminase (GPT) is used as a marker of liver disease due to the release of GPT into the blood following liver cell necrosis.|
|Base Catalog Number||151191|
|Beilstein Registry Number||3562140|
|Biochemical Physiological Actions||Glutamic-pyruvic transaminase (GPT) is located in most cells in the body, but is found in highest concentrations in the liver.|
|Molecular Weight||272.257 g/mol|
|Personal Protective Equipment||Eyeshields, Gloves, Respirator filter|
|Specific Activity||~80 u/mg protein|
|Unit Definition||One unit will cause the transamination of 1.0 µmole of L-alanine per minute at pH 7.5 and 25 °C.|