Cart
 
In Stock

Fibronectin

Fibronectin

$161.40

Key features and details

Fibronectin

SKU: 02150025-CF

Synonyms
CIG; Cold insoluble globulin
CAS Number:
86088-83-7
EC Number:
289-149-2
MDL Number:
MFCD00131062
Product Description

Fibronectin

Application Notes

Fibronectin has been shown to stimulate the proliferation of rat osteoblasts in vitro; to induce odontoblast polarization and to regulate the differentiation of human dental pulp cells into odontoblasts. It has wide applications in cellular research into proliferation, differentiation, development and morphology. Precoating of glass, plastic and micro-carrier beads aids cell attachment, particularly those cell which are deficient in cell surface fibronectin. It has been reported that proteolytic digests of fibronectin are mitogenic for CH23 fibroblasts.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Glycoproteins

Specifications
SKU 02150025-CF
Alternate Names CIG; Cold insoluble globulin
Application Notes Fibronectin has been shown to stimulate the proliferation of rat osteoblasts in vitro; to induce odontoblast polarization and to regulate the differentiation of human dental pulp cells into odontoblasts. It has wide applications in cellular research into proliferation, differentiation, development and morphology. Precoating of glass, plastic and micro-carrier beads aids cell attachment, particularly those cell which are deficient in cell surface fibronectin. It has been reported that proteolytic digests of fibronectin are mitogenic for CH23 fibroblasts.
Base Catalog Number 150025
Biochemical Physiological Actions Domains of fibronectin bind with collagen, fibrin, heparin, and specific cell membrane receptors. The most notable domain, Arg-Gly-Asp can be recognized by integrins and mediates cell adhesion. Fibronectin is also widely involved in interactions such as the attachment and migration of many cell types, cytoskeletal assembly, tyrosine phosphorylation, and metastasis.
CAS # 86088-83-7
EC Number 289-149-2
Extinction Coefficient E1%= 12.9 (280 nm in 8 M urea-0.2 M NaOH)(Lit.)
Format Lyophilized powder
Isoelectric Point 5.5 - 6.3 (Lit.)
Personal Protective Equipment Eyeshields, Gloves, Respirator filter
Purity ≥90%
Source Bovine Plasma
Sterility Sterile Filtered
Typical Working Concentration Cell culture substratum at 1-5 μg/cm2 or 0.5-50 μg/mL
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Citations
Documents

Certificate of Analysis

Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis
Certificate of Analysis

Datasheet

Datasheet

Material Safety Datasheet

Material Safety Datasheet
en_AE
Material Safety Datasheet
de_AT
Material Safety Datasheet
en_AU
Material Safety Datasheet
fr_BE
Material Safety Datasheet
en_CA
Material Safety Datasheet
fr_CA
Material Safety Datasheet
de_CH
Material Safety Datasheet
cn_ZH
Material Safety Datasheet
de_DE
Material Safety Datasheet
es_ES
Material Safety Datasheet
en_EU
Material Safety Datasheet
fi_FI
Material Safety Datasheet
fr_FR
Material Safety Datasheet
en_GB
Material Safety Datasheet
tw_ZH
Material Safety Datasheet
en_ID
Material Safety Datasheet
en_IE
Material Safety Datasheet
en_IN
Material Safety Datasheet
ja_JP
Material Safety Datasheet
de_LI
Material Safety Datasheet
de_LU
Material Safety Datasheet
en_MT
Material Safety Datasheet
es_MX
Material Safety Datasheet
no_NO
Material Safety Datasheet
pt_PT
Material Safety Datasheet
sv_SE
Material Safety Datasheet
en_US