N-Propyl Gallate

Application Notes

n-Propyl gallate is used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antioxidant

SKU	02102747-CF
Alternate Names	Gallic Acid; Propyl Ester; Progallin P; n-Propyl Ester of 3,4,5-Trihydroxybenzoic Acid; Propyl gallate; n-Propyl-3,4,5-Trihydroxybenzoate; 3,4,5-Trihydroxybenzene-1-propylcarboxylate; 3.4.5-Tihydroxybenzoic acid n-propl ester
Application Notes	n-Propyl gallate is used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.
Base Catalog Number	102747
Beilstein Registry Number	1877976
Biochemical Physiological Actions	An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis. However, propyl gallate induced single strand breaks in DNA at concentrations higher than 0.25 μM when it was combined with copper concentrations at 5 μM and above. Another report, however, found that incubation of isolated rat hepatocytes with propyl gallate at concentrations of >1 mM induced cell killing, whereas, a lower concentration of propyl gallate > 0.5 mM resulted in a ladder formation of soluble low-molecular weight DNA fragments, characteristic of apoptosis.
Boiling Point	Decomposes (NTP, 1992)
CAS #	121-79-9
Density	1.21 (NTP, 1992)
EC Number	204-498-2
Extinction Coefficient	EmM = 10.2 (272 nm, 1 M HCl) (Lit.)
Flash Point	368° F (NTP, 1992)
Format	Powder
Hazard Statements	H302-H317
Melting Point	302° F (NTP, 1992)
Molecular Formula	C10H12O5
Molecular Weight	212.201 g/mol
Personal Protective Equipment	Dust mask , Eyeshields, Faceshields, Gloves
pH	pH = 6.3 (0.05% aqueous solution); pH = 5.9 (0.1% aqueous solution); pH = 5.7 (0.2% aqueous solution)
pKa	8.11 (Lit.)
RTECS Number	LW8400000
Safety Symbol	GHS07
Solubility	less than 1 mg/mL at 68° F (NTP, 1992)
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Density	7.3 (NTP, 1992) (Relative to Air)
Vapor Pressure	2.6X10-7 mm Hg at 25 deg C (est)