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Hydrocortisone's primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. It also decreases bone formation. Various synthetic forms of cortisol are used to treat a variety of diseases.
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Corticosteroid | Cytokines | Growth Factors | Hormones
|Alternate Names||Cortisol; 17-Hydroxycorticosterone; Kendall's Compound F; 4-Pregnene-11b,17a,21-triol-3,20-dione; Reichstein's Substance M; 11b,17a,21-Trihydroxypregn-4-ene-3,20-dione; δ4-Pregnen-11β,17α,21-triol-3,20-dione|
|Application Notes||Hydrocortisone's primary functions are to increase blood sugar through gluconeogenesis; suppress the immune system; and aid in fat, protein and carbohydrate metabolism. It also decreases bone formation. Various synthetic forms of cortisol are used to treat a variety of diseases.|
|Base Catalog Number||101996|
|Beilstein Registry Number||1354819|
|Biochemical Physiological Actions||Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency.|
|Melting Point||220 °C|
|Molecular Weight||362.466 g/mol|
|Optical Rotation||+160 ± 10 ° (c=1, methanol)|
|Personal Protective Equipment||Eyeshields, Full-face particle respirator, Gloves, Respirator cartridge, Respirator filter|
|Solubility||Water Solubility320 mg/L (at 25 °C)|
|Sterilization of Solutions||Solutions can be sterile filtered using a 0.2 µm membrane.|
|Typical Working Concentration||Typical stock solutions can be prepared at concentrations of 50-500 mg solid (total powder) in 1 mL water|
|UV Visible Absorbance||241 ± 3 nm (methanol)|
|Vapor Pressure||1.35X10-13 mm Hg at 25 deg C (est)|