Okadaic acid, sodium salt, 100 μg
Okadaic Acid Sodium Salt
Application Notes
Okadaic acid has been used to study various cellular processes such as the cell cycle and apoptosis including microtubule organization and tau hosphorylation. This phosphatase inhibitor has also played a role in the study of nitric oxide metabolism and calcium signaling. In addition, okadaic acid has been shown to activate transcription of the Cox-2 gene, disrupt golgi, arrest transport in the rough endoplasmic reticulum, and affect neurotransmitter release.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Inhibitor of type 1 and 2A protein phosphatases | Tumor promotor
| SKU | 0215897480 |
| Alternate Names | OA; 9,10-deepithio-9,10-didehydroacanthifolicin |
| Application Notes | Okadaic acid has been used to study various cellular processes such as the cell cycle and apoptosis including microtubule organization and tau hosphorylation. This phosphatase inhibitor has also played a role in the study of nitric oxide metabolism and calcium signaling. In addition, okadaic acid has been shown to activate transcription of the Cox-2 gene, disrupt golgi, arrest transport in the rough endoplasmic reticulum, and affect neurotransmitter release. |
| Base Catalog Number | 15897480 |
| Biochemical Physiological Actions | Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. |
| CAS # | 78111-17-8 |
| Hazard Statements | H301-H311-H315-H331 |
| Melting Point | 171-175 deg C; 164-166 deg C |
| Molecular Formula | C44H67O13Na |
| Molecular Weight | 805.015 g/mol |
| Pack Size | 100 μg |
| Preparation Method | Preparation: Isolated from cultured Prorocentrum concavum by preparative flash, medium pressure and high performance liquid chromatography. Salf form generated in aqueous sodium hydroxide methanol solution. |
| Purity | ≥98% |
| RTECS Number | AA8227800 |
| Safety Symbol | GHS06 |
| Solubility | Readily soluble in many organic solvents, degrading in acid or base. |
| Source | Prorocentrum concavum |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
![DS [02158974]](https://www.mpbio.com/static/version20201229105009Z/frontend/Mpbio/default/en_US/images/pdf.png "DS [02158974]")