Ampicillin Sodium Salt
Ampicillin sodium salt is used to select for ampicillin resistance in mutated and transformed cells. It is also described for the use of inhancing luminol chemiluminescence.
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|Alternate Names||D[-]-α-Aminobenzylpenicillin; 6-[D(-)-α-Aminophenylacetamido]penicillanic acid; D-(−)-α-Aminobenzylpenicillin sodium salt; Aminobenzylpenicillin sodium salt|
|Application Notes||Ampicillin sodium salt is used to select for ampicillin resistance in mutated and transformed cells. It is also described for the use of inhancing luminol chemiluminescence.|
|Base Catalog Number||19419950|
|Beilstein Registry Number||4119211|
|Biochemical Physiological Actions||A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.|
|Molecular Weight||371.387 g/mol|
|Pack Size||50 mg|
|Personal Protective Equipment||Dust mask, Eyeshields, Faceshields, Gloves|
|pKa||At 25 °C ,pKa = 2.5 (-COOH),pKa = 7.3 (-NH2) (Lit.)|
|Sterilization of Solutions||Autoclaving solutions of ampicillin will destroy activity. Solutions can be sterilized by filtration (0.22 um filter) and stored frozen (-20 °C or below). Frozen solutions can be stored for up to 3 months.|
|Typical Working Concentration||100 mg/liter for both gram positive and gram negative bacteria|