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Synaptophysin is a calcium-binding and integral membrane glycoprotein present in presynaptic vesicles in almost all neurons. Synaptophysin has four transmembrane domains and it forms a complex with dynamin at high calcium concentrations suggesting an involvement in synaptic vesicle endocytosis.Synaptophysin is currently the most widely used marker for nerve terminals and for differentiating neuroendocrine tumors.
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|Antibody Type||Polyclonal Antibody|
|Application Notes||Immunoblotting; Immunostaining|
|Base Catalog Number||10706|
|Immunogen||Synthetic human synaptophysin|
|Pack Size||250 µL|
|Solubility||Soluble in Water|
|Specificity||Reactive in human and rat|
|Typical Working Concentration||Dilution:1:50 - 1:100|