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8-Methoxypsoralen

8-Methoxypsoralen

Synonyms 8-MOP; 9-Methoxyfuro[3,2-g][1]benzopyran-7-one; Ammoidin; Methoxsalen; Xanthotoxin

CAS Number: 298-81-7 Molecular Formula: C12H8O4 Molecular Weight: 216.192 g/mol

Beilstein Registry Number: 196453 EC Number: 206-066-9 MDL Number: MFCD00005009

SKU 02103296-CF
$191.95
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Description

Product Description

8-Methoxypsoralen

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Specifications
SKU 02103296-CF
Alternate Names 8-MOP; 9-Methoxyfuro[3,2-g][1]benzopyran-7-one; Ammoidin; Methoxsalen; Xanthotoxin
Base Catalog Number 103296
Beilstein Registry Number 196453
Biochemical Physiological Actions 8-methoxypsoralen (8-MOP) plus ultraviolet A (UVA) irradiation induces monoadducts and interstrand cross-links in DNA and therefore can be used to study DNA repair and recombination mechanisms. Cultured normal human melanocytes treated with 8-methoxypsoralen and irradiated with ultraviolet A (UVA) formed 8-methoxypsoralen-phospholipid photoadducts that could be substituted for diacylglycerol to activate protein kinase C in a cell-free system. 8-MOP is an inactivator of purified reconstituted cytochrome P450. It also inhibits substance P-induced histamine release from substance P-activated rat peritoneal mast cells by suppressing the rise in [Ca2+].
CAS # 298-81-7
EC Number 206-066-9
Extinction Coefficient EmM = 22.4 (249 nm), 11.5 (300 nm) (ethanol)(Lit.)
Format Powder
Hazard Statements H302-H334
Melting Point 298° F (NTP, 1992)
Molecular Formula C12H8O4
Molecular Weight 216.192 g/mol
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
pH pH = 5.5
Purity ≥99%
RTECS Number LV1400000
Safety Symbol GHS07, GHS08
Solubility less than 1 mg/mL at 59° F (NTP, 1992)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Pressure 2.15X10-6 mm Hg at 25 deg C (est)