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8-(4-Chlorophenylthio)-adenosine, 50 mg
cAMP analog which activates cAMP- and cGMP- dependent protein kinase.
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
|Alternate Names||8-CPT cAMP|
|Base Catalog Number||15889150|
|Biochemical Physiological Actions||Membrane permeable cAMP analog. Used as a selective activator of cAMP dependent protein kinase (PKA). Inhibits cGMP-dependent phosphodiesterase and, at higher concentrations, inhibits cAMP-dependent phosphodiesterase. Inhibits phosphoinositide hydrolysis and secretion stimulated by n-formyl-Met-Leu-Phe but not platelet-activating factor in leukocytes. Renders HL-60 cells more resistant to NO-induced DNA damage.|
|Extinction Coefficient||15.9 (281 nm in 0.1 M HCl)|
|Pack Size||50 mg|
|Personal Protective Equipment||Eyeshields, Gloves, respirator filter|
|Solubility||Soluble in water (25 mg/mL )|
|UV Visible Absorbance||λmax: 281nm|