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cAMP analog which activates cAMP- and cGMP- dependent protein kinase.
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|Alternate Names||8-CPT cAMP|
|Base Catalog Number||15889110|
|Biochemical Physiological Actions||Membrane permeable cAMP analog. Used as a selective activator of cAMP dependent protein kinase (PKA). Inhibits cGMP-dependent phosphodiesterase and, at higher concentrations, inhibits cAMP-dependent phosphodiesterase. Inhibits phosphoinositide hydrolysis and secretion stimulated by n-formyl-Met-Leu-Phe but not platelet-activating factor in leukocytes. Renders HL-60 cells more resistant to NO-induced DNA damage.|
|Extinction Coefficient||15.9 (281 nm in 0.1 M HCl)|
|Pack Size||10 mg|
|Personal Protective Equipment||Eyeshields, Gloves, respirator filter|
|Solubility||Soluble in water (25 mg/mL )|
|UV Visible Absorbance||λmax: 281nm|