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6-Aminonicotinamide, 1 g

6-Aminonicotinamide, 1 g

$123.20

SKU: 0215010301

Synonyms
6-Aminopyridine-3-carboxamide
CAS Number:
329-89-5
Molecular Formula:
C6H7N3O
Molecular Weight:
137.14
Beilstein Registry Number:
116042
EC Number:
206-349-7
MDL Number:
MFCD00006327
Packaging size:
1 g
Specifications
SKU 0215010301
Alternate Names 6-Aminopyridine-3-carboxamide
Application Notes 6-Aminonicotinamide was found to inhibit NADP+-dependent enzyme, 6-phosphogluconate dehydrogenase.
Base Catalog Number 15010301
Beilstein Registry Number 116042
Biochemical Physiological Actions 6-AN interferes with glycolysis, resulting in ATP depletion and synergizes with DNA-crosslinking chemotherapy drugs, like cisplatin, in killing cancer cells (IC50 = 0.5 mM). 6-AN also reduces cardiovascular oxidative injury following ischemia/reperfusion. In addition, 6-AN causes glial neurodegeneration.
CAS # 329-89-5
EC Number 206-349-7
Hazard Statements H360
Melting Point 240 - 250 °C
Molecular Formula C6H7N3O
Molecular Weight 137.14
Pack Size 1 g
Personal Protective Equipment Eyeshields, Gloves, respirator cartridges
RTECS Number US4550000
Safety Symbol GHS08
Solubility Soluble in warm methanol (0.2/20).
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Documents

Certificates of Analysis

Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)
Certificates of Analysis
English (United States)

Datasheets

Datasheets
English (United States)