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5-Fluorocytosine

5-Fluorocytosine

Synonyms 4-Amino-5-fluoro-2-hydroxypyrimidine; Flucystine; 4-amino-5-fluoro-2(1H)-pyrimidinone; Flucytosine

CAS Number: 2022-85-7 Molecular Formula: C4H4FN3O Molecular Weight: 129.094 g/mol

Beilstein Registry Number: 127285 EC Number: 217-968-7 MDL Number: MFCD00006035

SKU 02199792-CF
$619.30
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Description

Product Description

5-Fluorocytosine

Application Notes

5-Fluorocytosine is used in studies on TMP biosynthesis. It is used as an antifungal agent. It has also been used as a selection agent for plastids in transgenic plants.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Used in studies on TMP biosynthesis | Antifungal

Specifications
SKU 02199792-CF
Alternate Names 4-Amino-5-fluoro-2-hydroxypyrimidine; Flucystine; 4-amino-5-fluoro-2(1H)-pyrimidinone; Flucytosine
Application Notes 5-Fluorocytosine is used in studies on TMP biosynthesis. It is used as an antifungal agent. It has also been used as a selection agent for plastids in transgenic plants.
Base Catalog Number 199792
Beilstein Registry Number 127285
Biochemical Physiological Actions 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. 5-Fluorocytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis.
CAS # 2022-85-7
EC Number 217-968-7
Extinction Coefficient EmM= 8.91 (in 0.1 M HCl) (Lit.)
Format Powder
Hazard Statements H361
Melting Point 296 °C
Molecular Formula C4H4FN3O
Molecular Weight 129.094 g/mol
Personal Protective Equipment Eyeshields, Gloves, respirator filter
Purity ≥98.5%
RTECS Number HA6040000
Safety Symbol GHS08
Solubility >19.4 [ug/mL]
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
UV Visible Absorbance λ max (0.1 N HCl) 284 - 286 nm