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5-Azacytidine

5-Azacytidine

Synonyms 4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one; 5-Azacitidine; Ladakamycin

CAS Number: 320-67-2 Molecular Formula: C8H12N4O5 Molecular Weight: 244.207 g/mol

Beilstein Registry Number: 620461 EC Number: 206-280-2 MDL Number: MFCD00006539

SKU 02100821-CF
$36.00
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Description

Product Description

5-Azacytidine

Application Notes

5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Inhibition of protein synthesis | bacteriostatic | antitumor | mutagenic agent

Specifications
SKU 02100821-CF
Alternate Names 4-Amino-1-(β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one; 5-Azacitidine; Ladakamycin
Application Notes 5-Azacytidine, its incorporation into RNA alters RNA synthesis and processing, and results in inhibition of protein synthesis. It has been used as a cancer chemotherapeutic agent. It is a powerful bacteriostatic, antitumor, and mutagenic agent; it also exhibits immunosuppressive, antimitotic, radioprotective, and virostatic effects.
Base Catalog Number 100821
Beilstein Registry Number 620461
Biochemical Physiological Actions A potent growth inhibitor and cytotoxic agent; inhibits DNA methyltransferase, an important regulatory mechanism of gene expression, gene activation and silencing. Causes DNA demethylation or hemi-demethylation, creating openings that allow transcription factors to bind to DNA and reactivate tumor suppressor genes
CAS # 320-67-2
EC Number 206-280-2
Format Powder
Hazard Statements H302-H350
Melting Point 442 to 446° F (decomposes) (NTP, 1992)
Molecular Formula C8H12N4O5
Molecular Weight 244.207 g/mol
Personal Protective Equipment Eyeshields, full-face particle respirator , Gloves, respirator cartridge, respirator filter
RTECS Number XZ3017500
Safety Symbol GHS07, GHS08
Solubility >36.6 [ug/mL]
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.