Enjoy 30% off select life science products with free shipping and giveaways with promo code: RESEARCH30 Offer ends October 30, 2020.

Trichloroacetic acid

Trichloroacetic acid

Synonyms Trichloroethanoic Acid; TCA; Aceto-caustin; Acide trichloracetique; Acido tricloroacetico; Dow sodium inhibited; Konesta; Trichloressigsaeure; Varitox

CAS Number: 76-03-9 Molecular Formula: C2HCl3O2 Molecular Weight: 163.378 g/mol

Beilstein Registry Number: 970119 EC Number: 200-927-2 MDL Number: MFCD00004177

SKU 02190521-CF
$39.20
In Stock
Request a quote
Description

Product Description

Trichloroacetic Acid

Application Notes

Trichloroacetic acid is used in protein precipitation; has been used to determine protein concentration by quantitative precipitation. It is also Used as a decalcifier and fixative in microscopy. A protocol for the precipitation of nucleic acids can be found in Molecular Cloning. Rats exposed to chronic sublethal amounts of trichloroacetic acid displayed an increase in serum bilirubin with a decrease in hematological proteins and cholesterols along with significant decreases in red blood corpuscles, mean cell volume, mean corpuscular hemoglobin, hemoglobin and hematocrit. In mice the production of liver tumors was associated to Trichloroacetic acid, which is also a known mouse hepatocarinogen. On the guinea pig trichloroacetic acid was observed to be a mild alergen on the skin.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Decalcifier | Fixative | Determine protein concentration | Precipitation of Proteins

Specifications
SKU 02190521-CF
Alternate Names Trichloroethanoic Acid; TCA; Aceto-caustin; Acide trichloracetique; Acido tricloroacetico; Dow sodium inhibited; Konesta; Trichloressigsaeure; Varitox
Application Notes Trichloroacetic acid is used in protein precipitation; has been used to determine protein concentration by quantitative precipitation. It is also Used as a decalcifier and fixative in microscopy. A protocol for the precipitation of nucleic acids can be found in Molecular Cloning. Rats exposed to chronic sublethal amounts of trichloroacetic acid displayed an increase in serum bilirubin with a decrease in hematological proteins and cholesterols along with significant decreases in red blood corpuscles, mean cell volume, mean corpuscular hemoglobin, hemoglobin and hematocrit. In mice the production of liver tumors was associated to Trichloroacetic acid, which is also a known mouse hepatocarinogen. On the guinea pig trichloroacetic acid was observed to be a mild alergen on the skin.
Base Catalog Number 190521
Beilstein Registry Number 970119
Boiling Point 385 to 387° F at 760 mm Hg (NTP, 1992)
CAS # 76-03-9
Density 1.62 at 77° F (NTP, 1992)
EC Number 200-927-2
Flash Point greater than 230° F (NTP, 1992)
Format Powder
Hazard Statements H314-H410
Melting Point 135 to 136° F (NTP, 1992)
Molecular Formula C2HCl3O2
Molecular Weight 163.378 g/mol
Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter
pH pH of 0.1 molar aq solution: 1.2
Refractive Index n20/D 1.62(Lit.)
RTECS Number AJ7875000
Safety Symbol GHS05, GHS09
Solubility greater than or equal to 100 mg/mL at 72° F (NTP, 1992)
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Vapor Density 5.6 (NTP, 1992) (Relative to Air)
Vapor Pressure 1 mm Hg at 123.8° F ; 5 mm Hg at 168.8° F (NTP, 1992)