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Freund's incomplete adjuvant, 25 mL

Freund's incomplete adjuvant, 25 mL
S$113.92

Key features and details

Freund's Incomplete Adjuvant is a commonly used immunological adjuvant that contains non-metabolizable oils (paraffin oil) and surfactant (Arlacel A). Components are thoroughly mixed in controlled proportions and autoclaved prior to being vialed.


Features of Freund's Incomplete Adjuvant (FIA):


  • Also called Incomplete Freund's Adjuvant (IFA).
  • FIA can be utilized to produce water-in-oil emulsions of antigens.
  • By forming a depot at the injection site and stimulating the production of antibody-producing plasma cells, FIA predominantly induces a Th2-biased response.
  • FIA is typically used for subsequent boost immunizations.

SKU: 0855829

Synonyms
Incomplete Freund's Adjuvant
Packaging size:
25 mL
Product Description

This product is a mixture of paraffin oil (90%) and Arlacel A (10%). Freund's Incomplete Adjuvant has been widely used as a potent adjuvant in immunization protocols and vaccine development.

Freund's Incomplete Adjuvant forms a stable emulsion with water and the antigen, allowing for slow release of the immunogen at the injection site. The slow release of antigen is thought to contribute to the high and long-lasting antibody response. This sustained exposure to the antigen promotes a robust and persistent immune response, resulting in a higher titer of antibodies against the immunogen.

Freund's Incomplete Adjuvant is commonly used in conjunction with subsequent boosts to enhance antibody titer after the initial immunization with Freund's Complete Adjuvant (SKU: 0855828 MP Biomedicals).

Application Notes

  • Freund's Incomplete Adjuvant is commonly used in the production of water-in-oil emulsions of immunogens, particularly for antibody production and vaccine development.
  • Incomplete Freund's Adjuvant, which does not contain mycobacteria, is often used for boost injections to avoid potential side effects.
  • Freund's Incomplete Adjuvant is commonly used as subsequent boost injections to increase antibody titer after the initial injection with Freund's Complete Adjuvant.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Freund's Incomplete Adjuvant is a potent adjuvant that plays a crucial role in enhancing the immune response to immunogens by promoting sustained release of the antigen at the injection site. This adjuvant has wide-ranging applications in immunization protocols and vaccine development, which have significantly contributed to the development of effective vaccines and immunotherapies.

Specifications
SKU 0855829
Alternate Names Incomplete Freund's Adjuvant
Application Notes
  • Freund's Incomplete Adjuvant is commonly used in the production of water-in-oil emulsions of immunogens, particularly for antibody production and vaccine development.
  • Incomplete Freund's Adjuvant, which does not contain mycobacteria, is often used for boost injections to avoid potential side effects.
  • Freund's Incomplete Adjuvant is commonly used as subsequent boost injections to increase antibody titer after the initial injection with Freund's Complete Adjuvant.
Base Catalog Number 55829
Format Oily Liquid
Formulation Details Yellow, oily
Pack Size 25 mL
Sterility Sterile
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Documents

Certificate of Analysis (COA)

Datasheet

Datasheet
Datasheet

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