Login / Sign Up
Cart
 

Freund's incomplete adjuvant

Freund's incomplete adjuvant
$40.20

Key features and details

Freund's Incomplete Adjuvant is a commonly used immunological adjuvant that contains non-metabolizable oils (paraffin oil) and surfactant (Arlacel A). Components are thoroughly mixed in controlled proportions and autoclaved prior to being vialed.


Features of Freund's Incomplete Adjuvant (FIA):


  • Also called Incomplete Freund's Adjuvant (IFA).
  • FIA can be utilized to produce water-in-oil emulsions of antigens.
  • By forming a depot at the injection site and stimulating the production of antibody-producing plasma cells, FIA predominantly induces a Th2-biased response.
  • FIA is typically used for subsequent boost immunizations.

SKU: 08642861-CF

Synonyms
Incomplete Freund's Adjuvant
Packaging size:
1 Box
Product Description

This product is a mixture of paraffin oil (90%) and Arlacel A (10%). Freund's Incomplete Adjuvant has been widely used as a potent adjuvant in immunization protocols and vaccine development.

Freund's Incomplete Adjuvant forms a stable emulsion with water and the antigen, allowing for slow release of the immunogen at the injection site. The slow release of antigen is thought to contribute to the high and long-lasting antibody response. This sustained exposure to the antigen promotes a robust and persistent immune response, resulting in a higher titer of antibodies against the immunogen.

Freund's Incomplete Adjuvant is commonly used in conjunction with subsequent boosts to enhance antibody titer after the initial immunization with Freund's Complete Adjuvant (SKU: 0864285-CF MP Biomedicals).

Application Notes

Lacks the mycobacteria found in Complete Freund's Adjuvant so it minimizes the side effects. For this reason, Incomplete Freund's Adjuvant is used for the boost injections.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Freund's Incomplete Adjuvant is a potent adjuvant that plays a crucial role in enhancing the immune response to immunogens by promoting sustained release of the antigen at the injection site.

This adjuvant has wide-ranging applications in immunization protocols and vaccine development, which have significantly contributed to the development of effective vaccines and immunotherapies.

Specifications
SKU 08642861-CF
Alternate Names Incomplete Freund's Adjuvant
Application Notes Lacks the mycobacteria found in Complete Freund's Adjuvant so it minimizes the side effects. For this reason, Incomplete Freund's Adjuvant is used for the boost injections.
Base Catalog Number 642861
Format Oily Liquid
Formulation Details Yellow, oily
Pack Size 1 Box
Preparation Method Product is a mixture containing mineral oil and Arlacel A. Components are thoroughly mixed in controlled proportions and autoclaved prior to being vialed.
Sterility Sterile
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Documents

Certificate of Analysis (COA)

Safety Data Sheets

English (United States)