(±)-Miconazole nitrate, 100 g

Name: (±)-Miconazole nitrate, 100 g
SKU: 0215169380
Price: 2246.35 USD

$2,246.35

Key features and details

(±)-Miconazole Nitrate

SKU: 0215169380

Synonyms

1-[2,4-Dichloro-β-([2,4-dichlorobenzyl]oxy)phenethyl]imidazole nitrate salt; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate salt; 1-[2,4-Dichloro-β-([2,4-dichloro- benzyl]oxy]phenethyl]imidazole

CAS Number:

75319-48-1

Molecular Formula:

C18H14Cl4N2O·HNO3

Molecular Weight:

479.135 g/mol

EC Number:

245-256-6

MDL Number:

MFCD00058161

Packaging size:

100 g

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Product Description

(±)-Miconazole Nitrate

Application Notes

(±)-Miconazole Nitrate is used topically and by intravenous infusion. It is used to inhibit cytochrome P450 and to study automated luminescence-based cytochrome P450 profiling.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antifungal

Specifications

SKU	0215169380
Alternate Names	1-[2,4-Dichloro-β-([2,4-dichlorobenzyl]oxy)phenethyl]imidazole nitrate salt; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate salt; 1-[2,4-Dichloro-β-([2,4-dichloro- benzyl]oxy]phenethyl]imidazole
Application Notes	(±)-Miconazole Nitrate is used topically and by intravenous infusion. It is used to inhibit cytochrome P450 and to study automated luminescence-based cytochrome P450 profiling.
Base Catalog Number	15169380
Biochemical Physiological Actions	Miconazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary for ergosterol biosynthesis. The inhibition of ergosterol results in increased cellular permeability causing leakage of cellular contents. Miconazole may also inhibit endogenous respiration, interact with phospholipids in the cell membrane, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and interfere with triglyceride and phospholipid biosynthesis.
CAS #	75319-48-1
EC Number	245-256-6
Format	Powder
Hazard Statements	H302-H317
Molecular Formula	C18H14Cl4N2O·HNO3
Molecular Weight	479.135 g/mol
Pack Size	100 g
Personal Protective Equipment	Dust mask, Eyeshields, Faceshields, Gloves
RTECS Number	NI4771000
Safety Symbol	GHS07
Solubility	26.3 [ug/mL]
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Documents

Certificate of Analysis (COA)

MP COA [151693] lot ID: QR11627

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Datasheet

DS [02151693]