Prostaglandin E2, ≥99%

Name: Prostaglandin E2, ≥99%
SKU: 02195461-CF
Price: 131.38 USD

$131.38

Key features and details

Prostaglandin E2

SKU: 02195461-CF

Synonyms

5Z,11α,13E,15S]-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; Dinoprostone; PGE2

CAS Number:

363-24-6

Molecular Formula:

C20H32O5

Molecular Weight:

352.471 g/mol

Beilstein Registry Number:

4709356

EC Number:

206-656-6

MDL Number:

MFCD00077861

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Product Description

Prostaglandin E2

Application Notes

Prostaglandin E2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Induces cervical ripening and parturition

Specifications

SKU	02195461-CF
Alternate Names	5Z,11α,13E,15S]-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic acid; Dinoprostone; PGE2
Application Notes	Prostaglandin E2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation.
Base Catalog Number	195461
Beilstein Registry Number	4709356
Biochemical Physiological Actions	Most biologically active prostaglandin. PGE2 induces cervical ripening and parturition; mediates bradykinin-induced vasodilation; regulates adenylyl cyclase. Tumor cells that over-express cyclooxygenase 2 display increased invasiveness, angiogenesis, and resistance to apoptosis that may be due to the PGE2-induced expression of angiogenic factors and stabilization of the anti-apoptotic protein, survivin.The effect of PGE2 on the immune system is mixed. It inhibits T cell activation in vitro, suggesting it is an immunosuppressant. However, in vivo, it appears to effect expansion of the Th17 subset and differentiation of the Th1 subset of T helper cells, marking it as an immunoactivator.
CAS #	363-24-6
EC Number	206-656-6
Format	Powder
Hazard Statements	H302-H360
Melting Point	67 °C
Molecular Formula	C20H32O5
Molecular Weight	352.471 g/mol
Personal Protective Equipment	Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator filter, respirator cartridges
Purity	≥99%
RTECS Number	UK8000000
Safety Symbol	GHS07, GHS08
Solubility	Water Solubility 58.1 mg/L
Source	Synthetic
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.