Α-Thrombin
Application Notes
Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. Thrombin has been used in a study to assess persistent hypocoagulability in patients with septic shock.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
| SKU | 02194921-CF |
| Alternate Names | Factor IIa; Thrombin from bovine plasma |
| Application Notes | Thrombin is used for site specific cleavage of recombinant fusion proteins containing an accessible thrombin recognition site for removal of affinity tags. Thrombin has been used in a study to assess persistent hypocoagulability in patients with septic shock. |
| Base Catalog Number | 194921 |
| Biochemical Physiological Actions | Serine protease that selectively cleaves Arg-Gly bonds in fibrinogen to form fibrin and fibrinopeptides A and B. |
| CAS # | 2594047 |
| Extinction Coefficient | E (1%/1 cm, 280nm): 19.5 (Lit.) |
| Format | Solution |
| Formulation Details | Supplied in 50% Glycerol/H2O (vol/vol) |
| Hazard Statements | H317-H315-H319-H334-H335 |
| Personal Protective Equipment | Respiratory protection: Breathing apparatus only if aerosol or dust is formed. Hand protection: Handle with gloves Skin and body protection: Usual safety precautions while handling the product will provide adequate protection against this potential effect. Eye protection: Safety glasses with side-shields Hygiene measures: Handle in accordance with good industrial hygiene and safety practice. |
| Safety Symbol | GHS07, GHS08 |
| Source | Bovine |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |