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<> }{*PENICILLIN G SODIUM SALT

<> }{*PENICILLIN G SODIUM SALT

Synonyms Benzylpenicillin sodium salt

CAS Number: 69-57-8 Molecular Formula: C16H17N2O4SNa Molecular Weight: 356.4

Beilstein Registry Number: 3834217 EC Number: 200-710-2 MDL Number: MFCD00069666

Packaging size: 1 MU

SKU 0210054801
Price:
$15.50
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Description

Product Description

Penicillin G sodium salt is a salt of Penicillin G. Penicillin G is a hydrophobic, β-lactam antibiotic produced by Penicillium spp. Penicillin G is also known as benzylpenicillin and contains a 6’ phenylacetyl side chain. In acid aqueous solutions, Penicillin is reported to decompose into penillic acid and penilloic acid.

Application Notes

Penicillin G sodium salt is used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility. It is used in cell culture alone as well as in combination with streptomcyin and other antibiotics. It is the drug of choice for Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus.

Usage Statement

Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Key Applications

Antibiotic||Inhibitor of bacterial cell wall synthesis

Specifications
SKU 0210054801
Application Notes Penicillin G sodium salt is used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility. It is used in cell culture alone as well as in combination with streptomcyin and other antibiotics. It is the drug of choice for Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus.
Beilstein Registry Number 3834217
Biochemical Physiological Actions Mode of Action: Inhibits bacterial cell wall synthesis; Antimicrobial spectrum: Gram-positive bacteria. Penicillin G inhibits cell wall synthesis by binding to penicillin binding proteins (PBPs), which inhibits peptidoglycan chain cross-linking. Penicillin G is stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases.
Chemical Class Antibiotics
EC Number 200-710-2
Hazard Statements H317-H334
Applications Antibiotic||Inhibitor of bacterial cell wall synthesis
Molecular Formula C<sub>16</sub>H<sub>17</sub>N<sub>2</sub>O<sub>4</sub>SNa
Molecular Weight 356.4
Pack Size 1 MU
Personal Protective Equipment Dust mask, Eyeshields, Faceshields, Gloves
Physical Appearance Powder
Potency ≥1,500 u/mg
Preparation Method To prepare Stock Solutions: Add the appropriate amount of powder to water while mixing (not the reverse), as adding water to the powders may result in insoluble mixtures that cannot be filtered without losing potency. If desired, the pH may be adjusted, but a basal media with greater than 2 g/L sodium bicarbonate can easily absorb up to 2% of an acidic antibiotic solution; therefore, an antibiotic solution with an acidic pH would not influence the pH of the media. After ensuring that the resultant solution is transparent, sterile filter and store in small aliquots at appropriate temperature until use. Prior to use of the media, aseptically add the appropriate amount of antibiotic to the basal media in order to obtain the required working concentration. Mix well and sterile filter if asepsis is believed to have been compromised.
Product Families Description Penicillin G sodium salt is a salt of Penicillin G. Penicillin G is a hydrophobic, β-lactam antibiotic produced by Penicillium spp. Penicillin G is also known as benzylpenicillin and contains a 6’ phenylacetyl side chain. In acid aqueous solutions, Penicillin is reported to decompose into penillic acid and penilloic acid.
Risk Phrases R:42/43
RTECS Number XH9800000
Safety Phrases S:22-36/37-45
Safety Symbol GHS08
Storage and Handling Store at +4 °C.
Typical Working Concentration Gram Positive Bacteria - 105 U/L
Usage Statement Research Use Only (RUO). Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.