Product Description
Oxytetracycline is a tetracycline analog.
Application Notes
Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). It is used for fluorescence measurements of hepatocytes.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antibiotic | Used for fluorescence measurements of hepatocytes
Specifications
| SKU | 0215179480 |
| Alternate Names | 5-Hydroxytetracycline Dihydrate |
| Application Notes | Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). It is used for fluorescence measurements of hepatocytes. |
| Base Catalog Number | 15179480 |
| Biochemical Physiological Actions | Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation. Oxytetracycline inhibits translation, which results in cell death. It binds to the 30S ribosomal subunit and prevents the amino-acyl Trna from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic so it can easily pass through a cell membrane and passively diffuses through channels in the bacterial membrane. |
| CAS # | 6153-64-6 |
| EC Number | 201-212-8 |
| Melting Point | 178.8-182.2 °C(Lit.) |
| Molecular Formula | C22H24N2O9 • 2H2O |
| Molecular Weight | 496.46 |
| Optical Rotation | -196.6° (0.1 N HCl), -2.1 (0.1 N NaOH), +26.5 (methanol) at 25 °C(Lit.) |
| Pack Size | 100 g |
| Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
| pH | 4.5 - 7.0(10% aq soln) |
| Solubility | Soluble in water or 1N Hydrochloric acid. |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Documents
Certificate of Analysis (COA)
![MP COA [151794] lot ID: QR13975](https://www.mpbio.com/static/version1742546773/frontend/Mpbio/default/en_US/images/document.png "MP COA [151794] lot ID: QR13975")
Datasheet
Datasheet