Ampicillin Sodium Salt
Application Notes
Ampicillin is a semi-synthetic derivative of penicillin that functions as a broad-spectrum antibiotic. It has been used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid. Also described for the use of enhancing luminol chemiluminescence.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Antibiotic
SKU | 02194526-CF |
Alternate Names | D[-]-a-Aminobenzylpenicillin; 6-[D(-)-a-Aminophenylacetamido]penicillanic acid |
Application Notes | Ampicillin is a semi-synthetic derivative of penicillin that functions as a broad-spectrum antibiotic. It has been used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid. Also described for the use of enhancing luminol chemiluminescence. |
Base Catalog Number | 194526 |
Beilstein Registry Number | 4119211 |
Biochemical Physiological Actions | Mode of Action: This is a ß-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane.Mode of Resistance: Administration with ß-lactamase cleaves the ß-lactam ring of Ampicillin and inactivates it. Antimicrobial Spectrum: Includes both gram-positive (similar to benzylpenicillin) and gram-negative bacteria (similar to tetracyclines and chloramphenicol. |
CAS # | 69-52-3 |
EC Number | 200-708-1 |
Grade | Cell Culture Grade |
Hazard Statements | H317-H334 |
Molecular Formula | C16H18N3O4SNa |
Molecular Weight | 371.387 g/mol |
Personal Protective Equipment | Dust mask , Eyeshields, Faceshields, Gloves |
pKa | 2.5 (-COOH), pKa = 7.3 (-NH2) |
Potency | ≥800 µg/mg |
RTECS Number | XH8400000 |
Typical Working Concentration | 100 mg/liter for both gram positive and gram negative bacteria. |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |