Experience unmatched versatility

MP Bio, the innovator in bead beating technology, developed a wide variety of specialized Lysing Matrix tubes to guarantee a thorough homogenization and cell lysis of any sample.

  • Optimal cell disruption of any sample : Size of the beads and their composition optimized according to the sample
  • A solution for any application : Unmatched versatility with 16 matrix compositions available in 2 ml, 4.5 ml, 15 ml, 50 ml tubes or 96-well plates
  • High reproducibility : Lysing Matrix tubes contain highly controlled size and quantity of beads and are certified DNase & RNAse free
  • No cross contamination : Single-use closed Lysing Matrix tubes
  • A gold standard for Life Science applications validated with + 5,000 publications : They fit any high-speed bead-beating machines
Lysing Matrix A

Lysing Matrix A

  • All Sample Types
  • Animal tissues and cells
  • Bacteria
  • Yeasts and Fungi
  • Plants tissues and cells

Each impact-resistant tube contains garnet matrix and a 1/4 inch zirconium banded satellite. Lysing Matrix A can be used to lyse, grind or homogenize tough and resistant samples. Their use results in higher lysing efficiency for tough samples due to sharp, angular and irregular surfaces. Garnet matrix can be used very effectively for DNA isolation, but is very aggressive and should be used with caution for RNA and protein isolation applications. This grinding matrix is chemically inert and will not bind nucleic acids.

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Lysing Matrix B

Lysing Matrix B

  • Bacteria Gram + and -
  • Bacterial Spores
  • Oocytes
  • Prokaryotes
  • Archea

Each impact-resistant tube contains 0.1 mm silica spheres. Lysing Matrix B is used primarily for lysis of gram positive and gram negative bacteria, and to disrupt fungal tissue and spores. This matrix may also be used as an additive for disruption by sonication.

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Lysing Matrix C

Lysing Matrix C

  • Yeast and Fungi
  • Yeast and Fungal Spores
  • Algae

Each impact-resistant tube contains 1 mm silica spheres. Lysing Matrix C is used primarily for lysing yeast, fungi and spores, as well as mold and algae.

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Lysing Matrix D

Lysing Matrix D

  • Plant Tissues
  • Animal Tissues
  • Cultured Cells
  • Soft Tissue

Each impact-resistant tube contains 1.4 mm ceramic spheres. Lysing Matrix D is used primarily for lysis of softer tissues like brain, liver, kidney, lung, and spleen. Also used to lyse plant tissue such as leaves, roots, and fruits, as well as cultured cells and whole insects. This grinding matrix is chemically inert and will not bind nucleic acids.

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Lysing Matrix E

Lysing Matrix E

  • Soil
  • Feces
  • Environmental and Waste Water
  • Sludge
  • Pollen

Each impact-resistant tube contains 1.4 mm ceramic spheres, 0.1 mm silica spheres, and 4 mm glass beads. Lysing Matrix E is primarily used for environmental samples such as soil, sludge, wastewater and feces. Lysing Matrix E is also effective when working with mixed samples, such as microbially-infected tissue, and can be used in RNA extraction from tumors and other difficult tissues.

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Lysing Matrix F

Lysing Matrix F

  • Plant Tissues
  • Animal Tissues
  • Bacteria Gram + and -
  • Molds and Fungi
  • Coral emulsions
  • Fixed Samples

Each impact-resistant tube contain 1.6 mm aluminum oxide granules and 1.6 mm silicon carbide granules. For RNA and protein isolation for samples in which Matrix A is too aggressive. For isolation of intact organelles and super-molecular structures, tissues with brittle cell walls, bacteria (Gram +/-), molds and fungi, coral emulsions, and fixed samples where lower shearing is needed.

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Lysing Matrix G

Lysing Matrix G

  • Plant Tissues
  • Animal Tissues
  • Yeast and Fungi
  • Spores

Each impact-resistant tube contains 1.6 mm silicon carbide granules and 2 mm glass beads. For isolation of intact organelles, and super-molecular structures, breaking yeast polysaccharide capsules, hyphae infected tissue, tissues with brittle cell walls, fungal spores; where high impaction but low shearing is necessary.

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Lysing Matrix H

Lysing Matrix H

  • Plant and Animal Tissues
  • Wood and Seeds
  • Bacterial Aggregates
  • Whole Insects
  • Ticks, Fleas
  • Ancient and Dried Samples

Each impact-resistant tube contains 2 mm glass and 2 mm yellow zirconium oxide beads. ZrO2 has high density, tensile strength and hardness, and breaks very tough and hard plant/animal tissues, wood/seeds, dense soils/clays, bacterial aggregates/biofilms, insects/ticks, ancient and dried samples; where lysis conditions necessitate high impaction but low shearing.

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Lysing Matrix I

Lysing Matrix I

  • Plant and Animal Tissues
  • Wood and Seeds
  • Very Dense Soils and Clays
  • Whole Insects
  • Ticks, Fleas
  • Ancient and Dried Samples
  • Dry Fungal Spores/Rusts

Each impact-resistant tube contains 2 mm yellow zirconium oxide and 4 mm black ceramic beads. ZrO2 has high density, tensile strength and hardness, and breaks hard samples with a dense exterior matrix. Ceramic gives high inertia to break chitin/protein in exoskeleton of arthropods/ crustaceans. Use to isolate RNA/Proteins from plant/animal, dense soils/clays, insects, and dry grinding fungal spores/rusts.

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Lysing Matrix J

Lysing Matrix J

  • Plant and Animal Tissues
  • Bacteria Gram + and -
  • Fungi
  • Coral Emulsions
  • Fixed Samples
  • Dry Fungal Spores/Rusts

Each impact-resistant tube contains 2 mm yellow zirconia beads and 1.6 mm aluminum oxide granules. Will break bacterial spores or cysts inside infected tissue. The mixture of large and small diameter particles is also effective at "scrubbing" and lysing target cells that are fixed to a matrix such as tape-stripped skin cancer cells.

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Lysing Matrix K

Lysing Matrix K

  • Non-viable Tissues
  • Bone
  • Preserved Tissues
  • Animal By-Products
  • Fungal and Yeast Spores

Each impact-resistant tube contains 0.8 mm zirconium silicate beads. Found in the GENECLEAN™ for Ancient DNA Kit. Effective at breaking very tough and hard samples. The small spheres are also effective in breaking fungal spores, cysts, and yeast polysaccharide capsules, non-viable Tissues, Bone, Preserved Tissues, Animal By-products.

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Lysing Matrix M

Lysing Matrix M

  • All Samples
  • Tough Tissues
  • Skeletal Muscle
  • Lung
  • Heart
  • Bone
  • Seeds

Each impact-resistant tube contains one 1/4" (6.35 mm) diameter Zirconium Oxide banded satellite. Use to break hard/brittle samples. Applications include RNA extraction from samples where lysis by impaction is preferable with low mechanical shearing. Matrix is chemically inert and will not bind nucleic acids.

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Lysing Matrix S

Lysing Matrix S

  • All Samples
  • Tough Tissues
  • Skeletal Muscle
  • Lung
  • Heart
  • Bone
  • Seeds
  • Spores

Each impact-resistant tube contains six (6) 1/8" (3.175 mm) stainless-steel grinding beads. Use to break hard/brittle samples. Applications include RNA from samples where lysis by impaction is preferable with minimal amounts of mechanical shearing.

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Lysing Matrix SS

Lysing Matrix SS

  • All Samples
  • Tough Tissues
  • Skeletal Muscle
  • Lung
  • Heart
  • Bone
  • Seeds
  • Spores

Each impact-resistant tube contains 1/4'' (6.35mm, .25 cal) stainless-steel grinding balls. Use to break hard/brittle samples. Applications include RNA extraction from difficult samples where lysis by impaction only is preferable with minimal amounts of mechanical shearing.

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Lysing Matrix Y

Lysing Matrix Y

  • Bacteria Gram + and -
  • Yeast and Fungi
  • Yeast and Fungal spores
  • Algae
  • Biofilms
  • Yeasts with tougher cell walls

Each impact-resistant tube contains 0.5 mm diameter Yttria-Stabilized Zirconium Oxide beads which have high density and extremely high hardness. Ideal to break tough cell walls, its smooth surface minimizes shearing. In the FastRNA™ Spin Kit for Microbes and Yeast.

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Lysing Matrix Z

Lysing Matrix Z

  • Plant and Animal Tissues
  • Wood and Seeds
  • Very Dense Soils and Clays
  • Bacterial Aggregates
  • Whole Insects
  • Ticks, Fleas

Each impact-resistant tube contains 2.0 mm diameter Yttria-Stabilized Zirconium Oxide beads which have high density and hardness. Ideal to break tough cell walls, while its smooth surface minimizes shearing. Alternative to Matrix A as lower shear rates minimize degradation of RNA and Proteins.

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Metal Lysing Matrix Tubes

  • Environmental and Agriculture- Tough seeds such as Dried Corn, Soybeans, Wheat, Tomato and Chile; Wood,Bark, Roots, animal claws and hooves
  • Forensics- Bone, Teeth, Hair, Fingernails, non-Biological substrates
  • Cancer and Disease- Tough tissues, Bone, Cartilage, Skin
  • Industrial- Non Biological, Rocks and Minerals, Plastics and Composites, Printed Circuit Boards, Wood and Building Materials

Stainless Steel Lysing Matrix Tubes are ideal for grinding, lysis and homogenization of your most resistant samples! Constructed from 308 SS, these tubes and grinding matrix are tough enough to stand up to the most demanding mechanical punishment that can cause traditional thermoplastic tubes to crack. Our tubes are machined from premium grade billet and deliver superior strength over less expensive production methods such as deep-drawn aluminum tubes. An oblique angle conical bottom provides a better impact surface than the rounded bottoms of deep-drawn tubes. The stainless steel threaded cap provides a leak-proof closure without the energy-robbing alternatives like plastic flange screw caps or rubber stoppers. A Teflon O-ring prevents leakage, and can be cleaned with detergent and/or autoclaving, or replaced entirely between samples. Machined knurls on the cap provide a firm grip to easy opening and closing.

Two different impactors are available, a single Stainless Steel Ball, ¼” diameter; or a Stainless Steel Cylinder, ¼” diameter x ½” length.

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