Cell Culture Antibiotics: Keep Your Cell Cultures Contamination-Free
In cell culture, contamination of the culture media with microbiological organisms like bacteria, yeast, fungi, mycoplasma, and endotoxins can be extremely devastating, causing significant cell death and even catastrophic loss of the entire culture. The detrimental impact of microbiological contamination needs to be aggressively treated. Currently, the availability of antibiotics provides an excellent opportunity to combat cell culture contamination with minimal impact on the mammalian cells being cultured. Judicious selection of the antibiotic for your specific cell lines and culture conditions allows for full control of the media without altering cellular growth parameters.
Whether you require an antibiotic active against gram-positive bacteria, gram-negative bacteria, yeast, or fungi, MP Bio provides a wide range of high-quality antibiotics to treat your cell culture contamination.
- Easy to use – Convenient addition to liquid culture medium
- High potency – Keep your cell cultures contamination free
- Broad spectrum – Effective against a wide range of microbial contaminants
Penicillin-Streptomycin (20,000 IU Pen/mL, 20,000 µg Strep/mL)
Antibiotics used to prevent bacterial contamination of cell cultures.
The antibiotics penicillin and streptomycin are used to prevent bacterial contamination of cell cultures due to their effective combined action against gram-positive and gram-negative bacteria. This solution contains 10,000 units/mL of penicillin and 10,000 ug/mL of streptomycin.
Gentamicin Sul,10 mg/mL
Gentamicin is an aminoglycoside antibiotic complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is a mixture of 3 major components designated as C1 (C21H43N5O7), C1a (C19H39N5O), and C2 (C20H41N5O7). Gentamicin is used as the sulfate salt. Each component consists of five basic nitrogens and requires five equivalents of sulfuric acid per mole of gentamicin base. Gentamicin sulfate is a broad spectrum antibiotic. It inhibits the growth of a wide variety of Gram-positive and Gram-negative microorganisms, including strains resistant to tetracycline, chloramphenicol, kanamycin, and colistin, particularly strains of Pseudomonas, Proteus, Staphylococcus, and Streptococcus. It is effective against mycoplasma as well.
G418 Sulfate Solution
G418 Sulfate is an aminoglycoside related to Gentamicin and is toxic to bacteria, yeast,higher plants, mammalian cells, protozoans and helminths. The resistance genes are located on transposons Tn601(903) and Tn5 and are bacterial in derivation, but they can be expressed in eukaryotic cells. By introducing these genes into cells, resistance to G418 Sulfate is conferred. G418 Sulfate is an effective selecting agent utilized in killing prokaryotic and eukaryotic cells.
Amphotericin-B (250 µg/mL) 20 mL
Amphotericin B is a polyene antifungal antibiotic from Streptomyces sp. It has a high affinity for sterols, primarily ergosterols, of fungal and bacterial cell membranes. It is an antibiotic solution effective against yeast and other fungi. Amphotericin B may be toxic to some insect cell types. Amphotericin B, is an antimycotic.
The antibiotics penicillin and streptomycin are used to prevent bacterial contamination of cell cultures due to their effective combined action against gram-positive and gram-negative bacteria. This solution contains 10,000 units/mL of penicillin and 10,000 µg/mL of streptomycin.