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ISONICOTINIC ACID HYDRAZIDE

ISONICOTINIC ACID HYDRAZIDE

Synonyms Isoniazid; Isonicotinic hydrazide; INH; Isonicotinic acid hydrazide

CAS Number: 54-85-3 Molecular Formula: C6H7N3O Molecular Weight: 137.14

Beilstein Registry Number: 119374 EC Number: 200-214-6 MDL Number: MFCD00006426

Packaging size: 50 g

SKU 0210209650
Price:
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Specifications
SKU 0210209650
Application Notes Isonicotinic Acid Hydrazine is used for fluorescent HPLC detection of δ4-3-Ketosteroids. It can also used as antibiotic for treatment of Mycobacterium tuberculosis.
Beilstein Registry Number 119374
Biochemical Physiological Actions Isonicotinic Acid Hydrazine inhibits mycolic acid biosynthesis. Metabolized by hepatic N-acetyltransferase (NAT) and cytochrome P450 2E1 (CYP2E1) to form hepatotoxins. Selectively induces expression of CYP2E1. Reversibly inhibits CYP2C19 and CYP3A4 activities, and mechanistically inactivates CYP1A2, CYP2A6, CYP2C19 and CYP3A4 at clinically relevant concentrations.
Detection Method FTIR
EC Number 200-214-6
Hazard Statements H302-H315
Melting Point 165 - 175 °C
Molecular Formula C<sub>6</sub>H<sub>7</sub>N<sub>3</sub>O
Molecular Weight 137.14
Pack Size 50 g
Personal Protective Equipment Dust mask, Eyeshields, Gloves
pH 5.5 - 6.5(1% aq soln)
Physical Appearance White Powder
Related Products 05207836
Risk Phrases R:22-38
RTECS Number NS1751850
Safety Phrases S:36/37/39
Safety Symbol GHS07
Storage and Handling Store at Room Temperature (15-30 °C).
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.
UV Visible Absorbance λmax (water) 266 nm ± 5 nm