Sodium Orthovanadate

Application Notes

Sodium Orthovanadate is used in the diabetes study. Sodium orthovandate was used to prepare the stop solution in dephosphorylation assay of insulin receptor kinase. It was one of the reagents used in the development of Matrix ChIP that utilizes surface-immobilized antibodies.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Alkaline phosphate inhibitor

SKU	02159664-CF
Alternate Names	Decavanadate; Sodium Vanadate; Sodium Vanadium Oxide
Application Notes	Sodium Orthovanadate is used in the diabetes study. Sodium orthovandate was used to prepare the stop solution in dephosphorylation assay of insulin receptor kinase. It was one of the reagents used in the development of Matrix ChIP that utilizes surface-immobilized antibodies.
Base Catalog Number	159664
Biochemical Physiological Actions	Inhibits ATPase, alkaline phosphatase and tyrosine phosphatase. Decavanadate, which is formed at acidic pH, inhibits inositol 1,4,5-trisphosphate (IP3)-induced Ca2+ release from endocrine cells and blocks IP3 binding to its receptor in brain tissue.Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice. In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.
CAS #	13721-39-6
EC Number	237-287-9
Format	Powder
Hazard Statements	H302 + H312 + H332
Molecular Formula	Na3VO4
Molecular Weight	183.907 g/mol
Personal Protective Equipment	Dust mask , Eyeshields, Faceshields, Gloves
Purity	≥96%
RTECS Number	YW1120000
Safety Symbol	GHS07
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.