Ribostamycin sulfate salt, 100 mg

Product Description

Ribostamycin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit (some work by binding to the 50S subunit), inhibiting the translocation of the peptidyl-tRNA from the A-site to the P-site and also causing misreading of mRNA, leaving the bacterium unable to synthesize proteins vital to its growth.

Application Notes

It is used in pharmacokinetic and nephrotoxicity studies.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Antibiotic

Specifications

SKU	0215654380
Alternate Names	Landamycine; Ribomycine; Ribostamin; Ribostamycin Sulfate; SF 733 Antibiotic Sulfate; Vistamycin
Application Notes	It is used in pharmacokinetic and nephrotoxicity studies.
Base Catalog Number	15654380
Biochemical Physiological Actions	Aminoglycosides, such as ribostamycin, bind to the bacterial 30S and 50S ribosomal subunit, which inhibits the translocation of the peptidyl-tRNA from the A-site to the P-site. This causes misreading of mRNA which makes bacteria unable to make essential proteins. It also inhibits the chaperone activity of protein disulfide isomerase (PDI).
CAS #	53797-35-6
EC Number	258-783-1
Hazard Statements	H312-H332-H360
Pack Size	100 mg
Personal Protective Equipment	Eyeshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter
RTECS Number	WK2300000
Safety Symbol	GHS07, GHS08
Solubility	Soluble in water (200 mg/4 mL-clear, colorless solution).
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Documents

Datasheet

DS [02156543]