Cholic Acid Sodium Salt

Application Notes

Cholic acid is used in the solubilization of membrane-bound proteins in their native state. It is a component for the preparation of liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

SKU	02102897-CF
Alternate Names	Cholalic acid sodium salt; 3a,7a,12a-Trihydroxycholan-24-oic acid sodium salt; Sodium cholate; 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt
Application Notes	Cholic acid is used in the solubilization of membrane-bound proteins in their native state. It is a component for the preparation of liposomes. It has also been used in a study to investigate the elastic deformable vesicles, transfersomes, for transdermal drug delivery.
Base Catalog Number	102897
Beilstein Registry Number	3582354
Biochemical Physiological Actions	Cholate is a bile acid produced in liver during cholesterol breakdown. Cholate downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis). Cholate, an anionic detergent, is used alone and in combination with urea to extract and reconstitute membrane proteins and protein complexes.
CAS #	361-09-1
Critical Micelle Concentration	14 mM
EC Number	206-643-5
Molecular Formula	C24H39O5Na
Personal Protective Equipment	Eyeshields, Gloves, respirator filter
Purity	≥98%
RTECS Number	FZ9600000
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.