Guanine is one of the four main nucleobases found in the nucleic acids DNA and RNA. Guanine is a purine derivative.
Application Notes
Guanine is used as an additive to various products (e.g., shampoos), where it provides a pearly iridescent effect. It is also used in metallic paints and simulated pearls and plastics. It provides shimmering luster to eye shadow and nail polish. Guanine is suitable reagent used to investigate the mechanism of electrochemical oxidation of guanine and adenine using a glassy carbon microelectrode and cyclic and differential pulse voltammetry. It may be used in the preparation of mixed-sequence peptide nucleic acid (PNA) monomers.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Additive
SKU | 0219069101 |
Alternate Names | 2-Amino-6-hydroxypurine; 2-Amino-1,7-dihydro-6H-purin-6-one; 2-Aminohypoxanthine |
Application Notes | Guanine is used as an additive to various products (e.g., shampoos), where it provides a pearly iridescent effect. It is also used in metallic paints and simulated pearls and plastics. It provides shimmering luster to eye shadow and nail polish. Guanine is suitable reagent used to investigate the mechanism of electrochemical oxidation of guanine and adenine using a glassy carbon microelectrode and cyclic and differential pulse voltammetry. It may be used in the preparation of mixed-sequence peptide nucleic acid (PNA) monomers. |
Base Catalog Number | 19069101 |
Beilstein Registry Number | 9680 |
Biochemical Physiological Actions | It is reported to assemble into square-planar groups that resemble macrocycles, in which the bases interact via hydrogen bonds. In DNA and RNA, stretches of guanine bases are reported to form stable four stranded helices in the presence of sodium or potassium ions. The electrochemical oxidation of guanine has been studied in aqueous media at various carbon electrodes. It reacts with peroxynitrite under physiological conditions to afford 8-nitroguanine. |
CAS # | 73-40-5 |
EC Number | 200-799-8 |
Hazard Statements | H315-H317-H319-H335 |
Melting Point | > 360 °C(Lit.) |
Molecular Formula | C5H5N5O |
Molecular Weight | 151.13 |
Pack Size | 1 g |
Personal Protective Equipment | Dust mask, Eyeshields, Gloves |
RTECS Number | MF8260000 |
Safety Symbol | GHS07 |
Solubility | Soluble in 0.1 N HCl (50 mg/mL - clear, colorless solution), 1 M Sodium hydroxide (50 mg/mL - clear to slightly hazy light yellow solution). Freely soluble in ammonia water, aqueous KOH solutions, dilute acids; sparingly soluble in alcohol, ether. Almost insoluble in water. |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
UV Visible Absorbance | λ max (0.1N HCl) 245 - 250 nm |