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Dexamethasone 21-acetate, 500 mg

Dexamethasone 21-acetate, 500 mg
€200.00

SKU: 0219004190

Synonyms
9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate; 9α-Fluoro-16α-methylprednisolone-21-acetate; Prednisolone F acetate
CAS Number:
1177-87-3
Molecular Formula:
C24H31FO6
Molecular Weight:
434.5
Beilstein Registry Number:
2342608
EC Number:
214-646-8
MDL Number:
MFCD00027407
Packaging size:
500 mg
Product Description

Dexamethasone 21-acetate is an anti-inflammatory glucocorticoid that induces the production of phospholipase A2 inhibitory protein (lipocortin). It also inhibits induction of nitric oxide synthase (IC50=5 nM). Dexamethasone has been shown to cause reduction in cyclin A and Cdk2 activity, inhibition of G1/S transition in osteoblasts and inhibition of phosphorylation of Rb protein. Dexamethasone has been observed to induce apoptosis in human thymocytes and eosinophils but to inhibit apoptosis in neutrophils.

Application Notes

Dexamethasone 21-acetate is a glucocorticoid anti-inflammatory agent.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Anti-inflammatory

Specifications
SKU 0219004190
Alternate Names 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate; 9α-Fluoro-16α-methylprednisolone-21-acetate; Prednisolone F acetate
Application Notes Dexamethasone 21-acetate is a glucocorticoid anti-inflammatory agent.
Base Catalog Number 190041
Beilstein Registry Number 2342608
Biochemical Physiological Actions An anti-inflammatory glucocorticoid.
CAS # 1177-87-3
EC Number 214-646-8
Hazard Statements H317
Melting Point 232 - 233.5 °C(lit.)
Molecular Formula C24H31FO6
Molecular Weight 434.5
Pack Size 500 mg
RTECS Number TU4050000
Safety Symbol GHS07
Solubility Soluble in acetone (100mg/mL - Clear, Colorless to Light Yellow Solution).
Usage Statement Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Documents

Certificate of Analysis (COA)

Safety Data Sheets

English (United States)