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Specifications
SKU | 0215645605 |
Alternate Names | SPDP; N-Succinimidyl 3-[2-pyridyldithio]-propionate |
Application Notes | 3-(2-Pyridyldithio)proprionic Acid N-Hydroxysuccinimide Ester is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity, which incorporates a disulfide bridge between the conjugated species. Typically, coupled initially to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5). Second coupling specific for molecules containing free sulfhydryl by thiol-disulfide exchange buffered at pH 8.0 (7.5-8.5). Alternately, this reagent may be used as a protected thiolating reagent following initial coupling and reduction of linker. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates. Incorporates 4 atom linker. |
Base Catalog Number | 15645605 |
Beilstein Registry Number | 1548137 |
CAS # | 68181-17-9 |
EC Number | 269-034-3 |
Hazard Statements | H315-H319-H335 |
Melting Point | 84-86 °C(Lit.) |
Molecular Formula | C12H12N2O4S2 |
Molecular Weight | 321.36 |
Pack Size | 5 mg |
Personal Protective Equipment | Dust mask, Eyeshields, Gloves |
Safety Symbol | GHS07 |
Solubility | Soluble in methanol,DMF, acetone (50 mg/ mL-clear colorless to faintly yellow solution); slightly soluble in water. |
Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Documents
Datasheet
Datasheet