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}{ ETHYLENEDIAMINETETRAACETIC

}{ ETHYLENEDIAMINETETRAACETIC

Synonyms EDTA; (Ethylenedinitrilo)tetraacetic acid; Edathamil; Ethylenedinitrilotetraacetic acid

CAS Number: 60-00-4 Molecular Formula: C10H16N2O8 Molecular Weight: 292.3

Beilstein Registry Number: 1716295 EC Number: 200-449-4 MDL Number: MFCD00003541

Packaging size: 100 g

SKU 0210167680
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Description

Product Description

Ethylenediamine Tetraacetic Acid is a polyamino carboxylic acid hexadentate ligand.

Application Notes

Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component.

Usage Statement

Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.

Key Applications

Chelating agent||Buffer Component

Specifications
SKU 0210167680
Application Notes Ethylenediamine tetraacetic acid (EDTA) is a calcium chelator used to eliminate inhibition of enzyme catalyzed reactions due to traces of heavy metals. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. EDTA prevents platelet aggregation and is therefore the preferred anticoagulant for platelet counts. It is an inhibitor of metalloproteases and metal-activated proteases. It acts as a chelator of the zinc ion in the active site of metalloproteases, but EDTA can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. EDTA interferes with biological processes which are metal-dependent. It is a buffer component.
Auto Ignition > 200 °C (DIN 51794) (Lit.)
Beilstein Registry Number 1716295
Chemical Class Chelating Agents
Density ca. 860 kg/m<sup>3</sup> (bulk density) (Lit.)
Detection Method FTIR
EC Number 200-449-4
Flash Point > 100 °C (closed cup and DIN 51758) (Lit.)
Hazard Statements H319
Applications Chelating agent||Buffer Component
Melting Point 250 °C (dec.)(Lit.)/236 - 246 °C
Moisture Content <0.5%
Molecular Formula C<sub>10</sub>H<sub>16</sub>N<sub>2</sub>O<sub>8</sub>
Molecular Weight 292.3
Pack Size 100 g
Personal Protective Equipment Dust mask, Eyeshields, Gloves
pH 2.0 - 3.3 (saturated solution)
Physical Appearance White Powder
pKa 2.0, 2.7, 6.2, 10.3 (Lit.)
Product Families Description Ethylenediamine Tetraacetic Acid is a polyamino carboxylic acid hexadentate ligand.
Purity ≥99.0%
Related Products 02152521||02194659||04800682||04800683||04800684
Risk Phrases R:36/37/38-58
RTECS Number AH4025000
Safety Phrases S:20-25-26-29-37/39-61
Safety Symbol GHS07
Solubility Soluble in 3M NaOH (160 mg/mL); 1 M aq soln: Clear, Colorless & Complete, No Black Specks, Haze Free.
Storage and Handling Store at Room Temperature(15-30 °C).
Typical Working Concentration EDTA is an inhibitor of metalloproteases and metal-activated proteases at an effective concentration of 1-10 uM.
Usage Statement Research Use Only (RUO). Ready for CE IVD labeling of clinical applications.