Polymyxin B sulfate

Name: Polymyxin B sulfate
SKU: 02100565-CF
Price: 53 USD

Key features and details

Polymyxin B Sulfate

SKU: 02100565-CF

Synonyms

Aerosporin

CAS Number:

1405-20-5

Molecular Formula:

C55H96N16O13·2H2SO4

Molecular Weight:

1301.571 g/mol

EC Number:

215-774-7

MDL Number:

MFCD00131991

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Product Description

Polymyxin B Sulfate

Application Notes

Polymyxin B sulfate is a mixture of Polymyxin B1 and B2 sulfate. It is used clinically to treat infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of Pseudomonas aeruginosa. It is used to study multidrug-resistant pathogens.

Usage Statement

Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.

Key Applications

Cell culture

Specifications

SKU	02100565-CF
Alternate Names	Aerosporin
Application Notes	Polymyxin B sulfate is a mixture of Polymyxin B1 and B2 sulfate. It is used clinically to treat infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of Pseudomonas aeruginosa. It is used to study multidrug-resistant pathogens.
Base Catalog Number	100565
Biochemical Physiological Actions	Mode of Action: Polymyxin B Sulfate binds to the lipid A portion of bacterial lipopolysaccharides†, disrupting the cytoplasmic membrane by inducing pores large enough to permit nucleotide leakage in bacterial walls. This disrupts the permeability of the cytoplasmic membrane.Antimicrobial spectrum: Has bactericidal action on most gram-negative bacilli††, including E. Coli and on most fungi and gram-positive bacteria.
CAS #	1405-20-5
EC Number	215-774-7
Format	Powder
Hazard Statements	H302
Molecular Formula	C55H96N16O13·2H2SO4
Molecular Weight	1301.571 g/mol
Personal Protective Equipment	Dust mask, Eyeshields, Gloves
pKa	43227
RTECS Number	TR1150000
Solubility	Water Solubility25 mg/mL
Source	Soluble in water; 1 mM HCl
Storage	BIOCHEMICALS
Unit Definition	Effective concentration is typically 50 mg/L.
Usage Statement	Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.