Product Description
Cholesterol
Application Notes
Cholesterol is a component used for the preparation and study of artificial model membranes. One example is a study of valinomycin induced changes in membrane potentials of red blood cell and phospholipid (phosphatidylcholine from egg yolk plus cholesterol) vesicle suspensions. Positively charged cyanine dyes were used that fluorimetrically respond to the change in potential. Cholesterol is suitable for use in liposome preparations. It is standard for clinical work.
Usage Statement
Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department.
Key Applications
Cell Signaling | Metabolic Pathways
Specifications
| SKU | 02101382-CF |
| Alternate Names | 3β-Hydroxy-5-cholestene; 5-Cholesten-3β-ol; (3β)-cholest-5-en-3-ol |
| Application Notes | Cholesterol is a component used for the preparation and study of artificial model membranes. One example is a study of valinomycin induced changes in membrane potentials of red blood cell and phospholipid (phosphatidylcholine from egg yolk plus cholesterol) vesicle suspensions. Positively charged cyanine dyes were used that fluorimetrically respond to the change in potential. Cholesterol is suitable for use in liposome preparations. It is standard for clinical work. |
| Base Catalog Number | 101382 |
| Beilstein Registry Number | 1915888 |
| Biochemical Physiological Actions | Major component of all biological membranes; ~25% of total brain lipid is cholesterol. It is an essential structural component of mammalian cell membranes and is required to establish proper membrane permeability and fluidity. In addition to its importance within cells, cholesterol also serves as a precursor for the biosynthesis of steroid hormones, bile acids, and vitamin D. Cholesterol is the principal sterol synthesized by animals; in vertebrates it is formed predominantly in the liver. Small quantities are synthesized in other cellular organisms (eukaryotes) such as plants and fungi. It is almost completely absent among prokaryotes (i.e., bacteria). |
| Boiling Point | 360 °C |
| CAS # | 57-88-5 |
| Density | 1.067 @ 20 deg C/4 deg C |
| EC Number | 200-353-2 |
| Format | Powder |
| Melting Point | 148.5 °C |
| Molecular Formula | C27H46O |
| Molecular Weight | 386.664 g/mol |
| Optical Rotation | -34° to -42° |
| Pack Size | 1 Box |
| Personal Protective Equipment | Eyeshields, Gloves, Respirator filter |
| Purity | ≥99% |
| RTECS Number | FZ8400000 |
| Solubility | <h5 class="minor-section-title">Water Solubility</h5>0.095 mg/L (at 30 °C) |
| Storage | 2-8 °C |
| Usage Statement | Unless specified otherwise, MP Biomedical's products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
Documents
Certificate of Analysis (COA)
![MP COA [101382] lot ID: M3276](https://www.mpbio.com/static/version1742546773/frontend/Mpbio/default/en_US/images/document.png "MP COA [101382] lot ID: M3276")
Safety Data Sheets
English (United States)